Evidence map›Paper›PMID 31649720›Full record

ArticleFrontiers in genetics2019

A Population Genomics Analysis of the Native Irish Galway Sheep Breed.

Gillian P McHugo, Sam Browett, Imtiaz A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen D E Park, David A Magee, Erik Scraggs, Michael J Dover and 3 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Genetic Differentiation among Livestock Breeds-Values for FAnimals : an open access journal from MDPI · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gillian P McHugoAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Sam BrowettAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Imtiaz A S RandhawaSydney School of Veterinary Science, University of Sydney, Camden, NSW, Australia.
Dawn J HowardAnimal and Grassland Research and Innovation Centre, Athenry, Ireland.
Michael P MullenAnimal and Grassland Research and Innovation Centre, Athenry, Ireland.
Ian W RichardsonIdentiGEN Ltd., Blackrock Business Park, Dublin, Ireland.
Stephen D E ParkIdentiGEN Ltd., Blackrock Business Park, Dublin, Ireland.
David A MageeAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Erik ScraggsAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Michael J DoverAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Carolina N CorreiaAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
James P HanrahanAnimal and Grassland Research and Innovation Centre, Athenry, Ireland.
David E MacHughAnimal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Galway sheep population is the only native Irish sheep breed and this livestock genetic resource is currently categorised as 'at-risk'. In the present study, comparative population genomics analyses of Galway sheep and other sheep populations of European origin were used to investigate the microevolution and recent genetic history of the breed. These analyses support the hypothesis that British Leicester sheep were used in the formation of the Galway. When compared to conventional and endangered breeds, the Galway breed was intermediate in effective population size, genomic inbreeding and runs of homozygosity. This indicates that, although the Galway breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other breeds, which highlighted candidate genes that may be involved in production and health traits.

Indexed as

at-risk breedconservation genomicsgenetic diversityinbreedinglivestockselection signaturesingle nucleotide polymorphism

Identifiers

PMID31649720
PMCPMC6792165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.