Evidence map›Paper›PMID 31649684›Full record

ArticleFrontiers in immunology2019

Functional Change of Effector Tumor-Infiltrating CCR5

Pin-Yuan Chen, Caren Yu-Ju Wu, Jian-He Fang, Hsiu-Chi Chen, Li-Ying Feng, Chiung-Yin Huang, Kuo-Chen Wei, Jia-You Fang, Chun-Yen Lin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. CCR5 expression defines the functional heterogeneity of tumor-infiltrating CD8Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Pin-Yuan ChenDepartment of Neurosurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Caren Yu-Ju WuDepartment of Neurosurgery, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.
Jian-He FangDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Hsiu-Chi ChenDepartment of Neurosurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Li-Ying FengDepartment of Neurosurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chiung-Yin HuangDepartment of Neurosurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Kuo-Chen WeiDepartment of Neurosurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Jia-You FangPharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan.
Chun-Yen LinSchool of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chang Gung University of Science and Technology · TWChang Gung University · TWLinkou Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human glioma facilitates an impaired anti-tumor immunity response, including defects in circulation of T lymphocytes. The level of CD8

Indexed as

ADP-ribosyl Cyclase 1AdultCD8-Positive T-LymphocytesFemaleGliomaHLA-DR AntigensHumansMaleMembrane GlycoproteinsMiddle AgedReceptors, CCR5Tumor MicroenvironmentADP-ribosyl Cyclase 1CCR5 protein, humanCD38 protein, humanHLA-DR AntigensMembrane GlycoproteinsReceptors, CCR5CCL5CCR5CD8gliomaT cell

Identifiers

PMID31649684
PMCPMC6794477
OpenAlexW2979547654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.