Evidence map›Paper›PMID 31649646›Full record

ArticleFrontiers in microbiology2019

Microbial Metabolic Capacity for Intestinal Folate Production and Modulation of Host Folate Receptors.

Melinda A Engevik, Christina N Morra, Daniel Röth, Kristen Engevik, Jennifer K Spinler, Sridevi Devaraj, Sue E Crawford, Mary K Estes, Markus Kalkum, James Versalovic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 1 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Gut microbes · 2026
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  17. Mutual dosing of tungsten, molybdenum and selenium impact anaerobic digestion microbiome.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Melinda A EngevikDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Christina N MorraDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Daniel RöthDepartment of Molecular Imaging and Therapy, Beckman Research Institute of the City of Hope, Duarte, CA, United States.
Kristen EngevikDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Jennifer K SpinlerDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Sridevi DevarajDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Sue E CrawfordDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Mary K EstesDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Markus KalkumDepartment of Molecular Imaging and Therapy, Beckman Research Institute of the City of Hope, Duarte, CA, United States.
James VersalovicDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Baylor College of Medicine · USTexas Children's Hospital · USBeckman Research InstituteCity of Hope · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
Gut L-Histidine Metabolism and Histamine Signaling in Colonic NeoplasiaU01CA170930 · NCI · BAYLOR COLLEGE OF MEDICINE · PI VERSALOVIC, JAMES · 2013 to 2017
$2.8M
NCI NIH HHS P30 CA033572NCI NIH HHS U01 CA170930NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

Microbial metabolites, including B complex vitamins contribute to diverse aspects of human health. Folate, or vitamin B

Indexed as

B vitaminenteroidsfolate transportersfolylpolyglutamateLactobacilliLactobacillus reuterimicrobiome

Identifiers

PMID31649646
PMCPMC6795088
OpenAlexW2979838196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.