Evidence map›Paper›PMID 31649538›Full record

ArticleFrontiers in pharmacology2019

Anti-Cancer Effects of 3, 3'-Diindolylmethane on Human Hepatocellular Carcinoma Cells Is Enhanced by Calcium Ionophore: The Role of Cytosolic Ca

Yuanyue Jiang, Yanfei Fang, Yang Ye, Xinming Xu, Bingfang Wang, Jie Gu, Michael Aschner, Jian Chen, Rongzhu Lu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 44 citations in OpenAlex.

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  10. Common methods in mitochondrial research (Review).International journal of molecular medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yuanyue JiangDepartment of Preventive Medicine and Public Health Laboratory Science, School of Medicine, Jiangsu University, Zhenjiang, China.
Yanfei FangDepartment of Preventive Medicine and Public Health Laboratory Science, School of Medicine, Jiangsu University, Zhenjiang, China.
Yang YeDepartment of Preventive Medicine and Public Health Laboratory Science, School of Medicine, Jiangsu University, Zhenjiang, China.
Xinming XuDepartment of General Surgery, Affiliated Kunshan Hospital, Jiangsu University School of Medicine, Suzhou, China.
Bingfang WangDepartment of Digestive Disease, Affiliated Kunshan Hospital, Jiangsu University School of Medicine, Suzhou, China.
Jie GuInstitute of Life Science, Jiangsu University, Zhenjiang, China.
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, United States.
Jian ChenDepartment of General Surgery, Affiliated Kunshan Hospital, Jiangsu University School of Medicine, Suzhou, China.
Rongzhu LuDepartment of Preventive Medicine and Public Health Laboratory Science, School of Medicine, Jiangsu University, Zhenjiang, China.
Jiangsu University · CNFirst People's Hospital of Kunshan · CNAlbert Einstein College of Medicine · USShanghai University of Traditional Chinese Medicine · CN

Funding

Mechanisms of Methylmercury Induced Neuron ToxicityR01ES007331 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 1996 to 2026
$10.6M
Genetic Modulation of MeHg-Induced Oxidative Stress in the Developing BrainR01ES020852 · NIEHS · VANDERBILT UNIVERSITY · PI ASCHNER, MICHAEL · 2012 to 2016
$1.8M
NIEHS NIH HHS R01 ES007331NIEHS NIH HHS R01 ES020852
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3,3′-diindolylmethaneapoptosiscytosolic Ca2+hepatocellular carcinoma cellsp38 MAPKproliferation

Identifiers

PMID31649538
PMCPMC6795059
OpenAlexW2980199406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.