Evidence map›Paper›PMID 31649233›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2019

A Pilot Study of Third-Generation Dual-Source Computed Tomography for the Assessment of Global Dynamic Changes in Left Ventricular Structure and Function in a Porcine Model of Acute Myocardial Infarction.

Wenjia Li, Liang Lyu, Weixin Yang, Rongshun Zhang, Gang Wang, Dong Fang, Wei Song, Junkun Yin, Jiangmao Yang, Wei Li and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Wenjia LiChongqing Medical University, Chongqing, China (mainland).
Liang LyuDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Weixin YangDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Rongshun ZhangDepartment of Radiology, Third People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Gang WangDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Dong FangDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Wei SongDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Junkun YinDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Jiangmao YangDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Wei LiDepartment of Radiology, First People's Hospital of Yunnan, Kunming, Yunnan, China (mainland).
Liling ChenKunming Medical University, Kunming, Yunnan, China (mainland).
Tianyou LuoDepartment of Radiology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China (mainland).
First People's Hospital of Yunnan Province · CNChongqing Medical University · CNKunming Medical University · CNThird People's Hospital of Yunnan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND First-generation and second-generation dual-source computed tomography (DSCT) are useful for analyzing left ventricle (LV) structure and function. This pilot study aimed to investigate the feasibility and role of third-generation DSCT for the evaluation of dynamic changes in LV structural and functional characteristics in a Diannan small-ear pig model of acute myocardial infarction (AMI). MATERIAL AND METHODS The model of AMI was established by balloon occlusion of the distal third of the left anterior descending (LAD) coronary artery in 14 Diannan small-eared pigs. Third-generation DSCT was performed to observe dynamic changes in LV structure and function before and after AMI was induced, with a follow-up period of 30 days. RESULTS The mean structural measurements at baseline included interventricular septum thickness (8.50±0.90 mm), LV anterior wall thickness (8.40±1.30 mm), LV posterior wall thickness (7.80±1.20 mm), LV end-diastolic dimension (LVEDD) (45.00±4.90 mm), and LV end-systolic dimension (LVESD) (25.90±4.10 mm). The mean functional measurements at baseline included the LV end-diastolic volume (LVEDV) (74.62±13.54 ml), LV end-systolic volume (LVESV) (23.06±7.46 ml), LV ejection fraction (LVEF) (69.29±6.83%), LV mass (86.35±14.02 g), stroke volume (SV) (51.56±9.77 ml), and cardiac output (CO) (4.22±2.14 l/min). Trends of time-dependent changes were observed for LVESV, LVEF, SV, and CO, but not for LVEDV or LV mass. CONCLUSIONS Third-generation DSCT was validated as a tool for assessing dynamic changes in LV global function in a porcine model of AMI.

Indexed as

AnimalsCardiac OutputChinaDisease Models, AnimalHeart VentriclesMyocardial InfarctionPilot ProjectsStroke VolumeSwineTomography, X-Ray ComputedVentricular Function, Left

Identifiers

PMID31649233
PMCPMC6825397
OpenAlexW2982217043

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.