Evidence map›Paper›PMID 31649161›Full record

ArticleAJNR. American journal of neuroradiology2019

Novel Models for Identification of the Ruptured Aneurysm in Patients with Subarachnoid Hemorrhage with Multiple Aneurysms.

H Rajabzadeh-Oghaz, J Wang, N Varble, S-I Sugiyama, A Shimizu, L Jing, J Liu, X Yang, A H Siddiqui, J M Davies and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Single-stage endovascular treatment in aneurysmal subarachnoid haemorrhage with multiple intracranial aneurysms: Systematic review of the literature and multicentric retrospective experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

H Rajabzadeh-OghazFrom the Canon Stroke and Vascular Research Center (H.R.-O., N.V., A.H.S., J.M.D., H.M.).ORCID 0000-0002-9138-9239
J WangBiostatistics (J.W.), University at Buffalo, Buffalo, New York.ORCID 0000-0002-2709-5332
N VarbleFrom the Canon Stroke and Vascular Research Center (H.R.-O., N.V., A.H.S., J.M.D., H.M.).ORCID 0000-0003-2273-7962
S-I SugiyamaDepartment of Neuroanesthesia (S.-I.S.), Kohnan Hospital, Sendai, Japan.ORCID 0000-0002-0406-8307
A ShimizuDepartment of Neurosurgery (S.-I.S., A.S.), Tohoku University Graduate School of Medicine, Sendai, Japan.ORCID 0000-0001-9258-5250
L JingDepartment of Interventional Neuroradiology (L.J., J.L., X.Y., H.M.), Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-1655-7538
J LiuDepartment of Interventional Neuroradiology (L.J., J.L., X.Y., H.M.), Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-5454-2847
X YangDepartment of Interventional Neuroradiology (L.J., J.L., X.Y., H.M.), Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-7306-0125
A H SiddiquiFrom the Canon Stroke and Vascular Research Center (H.R.-O., N.V., A.H.S., J.M.D., H.M.).ORCID 0000-0002-9519-0059
J M DaviesFrom the Canon Stroke and Vascular Research Center (H.R.-O., N.V., A.H.S., J.M.D., H.M.).ORCID 0000-0002-5225-3072
H MengFrom the Canon Stroke and Vascular Research Center (H.R.-O., N.V., A.H.S., J.M.D., H.M.) huimeng@buffalo.edu.ORCID 0000-0003-3884-499X

Funding

Institutional Career DevelopmentKL2TR001413 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2015 to 2024
$4.2M
Virtual Intervention of Intracranial AneurysmsR01NS091075 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2019
$1.7M
AView: A Bedside Simulation Tool for Neurovascular InterventionR03NS090193 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2016
$157k
NCATS NIH HHS KL2 TR001413NINDS NIH HHS R01 NS091075NINDS NIH HHS R03 NS090193
6 · The paper itself

Abstract

background and purposeIn patients with SAH with multiple intracranial aneurysms, often the hemorrhage pattern does not indicate the rupture source. Angiographic findings (intracranial aneurysm size and shape) could help but may not be reliable. Our purpose was to test whether existing parameters could identify the ruptured intracranial aneurysm in patients with multiple intracranial aneurysms and whether composite predictive models could improve the identification. MATERIALS AND

methodsWe retrospectively collected angiographic and medical records of 93 patients with SAH with at least 2 intracranial aneurysms (total of 206 saccular intracranial aneurysms, 93 ruptured), in which the ruptured intracranial aneurysm was confirmed through surgery or definitive hemorrhage patterns. We calculated 13 morphologic and 10 hemodynamic parameters along with location and type (sidewall/bifurcation) and tested their ability to identify rupture in the 93 patients. To build predictive models, we randomly assigned 70 patients to training and 23 to holdout testing cohorts. Using a linear regression model with a customized cost function and 10-fold cross-validation, we trained 2 rupture identification models: RIM

resultsThe 25 study parameters had vastly different positive predictive values (31%-87%) for identifying rupture, the highest being size ratio at 87%. RIM

conclusionsSize ratio was the best individual factor for identifying the ruptured aneurysm; however, RIM

Indexed as

HemodynamicsAgedAlgorithmsAneurysm, RupturedAngiography, Digital SubtractionCerebral AngiographyFemaleHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalIntracranial AneurysmLinear ModelsMaleMiddle AgedRetrospective StudiesSubarachnoid Hemorrhage

Identifiers

PMID31649161
PMCPMC6871507

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.