Evidence map›Paper›PMID 31648973›Full record

ArticleThe lancet. Gastroenterology & hepatology2019

The global challenge of colorectal cancer.

Marianne Grønlie Guren

Registry-linked trialAbstract readComment
PubMed Publisher
In one paragraph

Article in The lancet. Gastroenterology & hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05590117 (The Possible Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer), which is not on this map. Cited by 76 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05590117 early_phase1unknown statusnot on this mapstarted 2022, after this paper: background citation

The Possible Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer

TypeinterventionalSponsorTanta UniversityRan2022 to 2024Enrolled48ConditionsColo-rectal Cancer, Neuropathy, Peripheral, MucositisArmsPentoxifylline, Placebo, FOLFOX-6 regimen
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A Colon Cancer Organoid-on-a-Chip Model for In Vitro Therapy Assessment.International journal of molecular sciences · 2026
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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Marianne Grønlie GurenDepartment of Oncology and K.G. Jebsen Colorectal Cancer Research Centre, Oslo University Hospital, 0424 Oslo, Norway. Electronic address: marianne.gronlie.guren@ous-hf.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colonic NeoplasmsColorectal NeoplasmsGlobal Burden of DiseaseHumansRisk Factors

Identifiers

PMID31648973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.