Evidence map›Paper›PMID 31648826›Full record

ArticleInternational journal of cardiology2020

High-intensity interval training for patients with coronary artery disease: Finding the optimal balance.

Andrew Keech, Katie Holgate, Jennifer Fildes, Praveen Indraratna, Leigh Cummins, Chaminda Lewis, Jennifer Yu

Abstract read
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Article in International journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Andrew KeechDepartment of Exercise Physiology, School of Medical Sciences, University of New South Wales, Sydney, Australia. Electronic address: andrew.keech@unsw.edu.au.
Katie HolgateCardiac Rehabilitation, Prince of Wales Hospital, Sydney, Australia.
Jennifer FildesCardiac Rehabilitation, Prince of Wales Hospital, Sydney, Australia.
Praveen IndraratnaDepartment of Cardiology, Prince of Wales Hospital and the Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
Leigh CumminsDepartment of Cardiology, Prince of Wales Hospital and the Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
Chaminda LewisDepartment of Respiratory Medicine, Prince of Wales Hospital, Sydney, Australia.
Jennifer YuDepartment of Cardiology, Prince of Wales Hospital and the Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal characteristics of high-intensity interval training (HIIT) for patients with coronary artery disease (CAD) within cardiac rehabilitation (CR) are unclear. We assessed a HIIT protocol designed to balance patient safety, efficacy and enjoyment.

methodsTwenty-nine patients with CAD completed 6-weeks (× 2 sessions per week) of HIIT within outpatient (phase 2) CR. HIIT comprised 15 repetitions × 30-seconds cycling at ∼85-90% maximum heart rate, interspersed with 30-seconds of active recovery. Key outcomes covered patient safety, efficacy (peak aerobic capacity, body composition, blood pressure and vascular function), and patient adherence and enjoyment.

resultsNo cardiovascular-related adverse events were reported in relation to HIIT sessions. Patients showed significant improvement in peak aerobic capacity (mean +12%, p < 0.001, effect size d = 0.38), blood pressure (brachial systolic -7mmHg, p < 0.001, d = -0.59) and total body fat (-4%, p < 0.001, d = -0.49). Central adaptations were prominent (aortic systolic BP -5mmHg, p = 0.001, d = -0.50; visceral fat -10%, p = 0.001, d = -0.41). Patient enjoyment of training was high (5.5 out of 7 using the Exercise Enjoyment Scale) and measures of affective state improved following training (assorted p < 0.018).

conclusionsThis HIIT protocol appears safe, effective and enjoyable for patients with CAD within CR. Improved aerobic fitness, blood pressure and body fat levels were observed indicating improved cardiovascular-risk. High patient enjoyment and improved mood suggest the HIIT could be sustainable for patients in the longer-term.

Indexed as

Outpatient Clinics, HospitalAdultAgedCardiac RehabilitationCoronary Artery DiseaseFeasibility StudiesFemaleHigh-Intensity Interval TrainingHumansMaleMiddle AgedProspective StudiesAerobicBlood pressureBody compositionCardiac rehabilitationCardiovascularExercisePhysical activitySafety

Identifiers

PMID31648826

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.