ArticleThe Korean journal of internal medicine2020
Low parathyroid hormone level predicts infection-related mortality in incident dialysis patients: a prospective cohort study.
Article in The Korean journal of internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06963853 (Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis), which is not on this map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Clinical characteristics and prognosis of peritoneal dialysis-associated peritonitis caused by non-fermenting Gram-negative bacteria: a single-center retrospective analysis.Renal failure · 2026Article
- Low Time-Weighted Parathyroid Hormone Is Associated with Malnutrition-Inflammation and Functional Dependence in Maintenance Hemodialysis.Nutrients · 2026Article
- Association between serum intact parathyroid hormone and survival in dialysis patients.International urology and nephrology · 2025Article
- Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study.Experimental and therapeutic medicine · 2025Article
- Article
- Relationship between serum iPTH and peritonitis episodes in patients undergoing continuous ambulatory peritoneal dialysis.Frontiers in endocrinology · 2023Article
- Is Adynamic Bone Always a Disease? Lessons from Patients with Chronic Kidney Disease.Journal of clinical medicine · 2022Review
- Article
- The current status of chronic kidney disease-mineral and bone disorder management in China.Scientific reports · 2022Article
- Low Parathyroid HormoneFrontiers in endocrinology · 2022Article
- The optimal range of serum intact parathyroid hormone for a lower risk of mortality in the incident hemodialysis patients.Renal failure · 2021Article
- Article
- Article
- Low serum parathyroid hormone is a risk factor for peritonitis episodes in incident peritoneal dialysis patients: a retrospective study.BMC nephrology · 2021Article
- Aberrant serum parathyroid hormone, calcium, and phosphorus as risk factors for peritonitis in peritoneal dialysis patients.Scientific reports · 2021Observational
- Hemodialysis patients with low serum parathyroid hormone levels have a poorer prognosis than those with secondary hyperparathyroidism.Therapeutic advances in endocrinology and metabolism · 2020Article
- BMD in peritoneal dialysis: what BRAZPD can help us understand?Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsParathyroid hormone (PTH) is an important factor influencing immunologic dysfunction, but the effect of PTH level on infection-related outcomes remains unclear in incident dialysis.
methodsWe evaluated a multicenter prospective cohort study of 1,771 incident dialysis patients (1,260 hemodialysis and 511 peritoneal dialysis) in Korea. Patients were divided into three groups based on serum intact PTH (iPTH) level. The primary outcomes were all-cause and infection-related mortality and multivariate Cox regression analysis was performed to evaluate the role of iPTH in all-cause and infection-related mortality.
resultsDuring the follow-up period of 27.3 months, 175 patients (9.9%) died, and infection-related death represented 20% of all-cause mortality. Both all-cause mortality and infection-related mortality rates (p < 0.001 and p = 0.003, by logrank) were markedly higher in patients with serum iPTH < 150 pg/mL than in the other groups. Multivariate Cox regression analysis revealed that patients with serum iPTH < 150 pg/mL remained at higher risk for infection-related mortality than patients in the target range of 150 ≤ iPTH < 300 pg/mL, after adjusting for confounding variables (hazard ratio [HR], 2.52; 95% confidence interval, 1.06 to 5.99; p = 0.04). The HR of infection-related mortality in patients with serum iPTH < 150 pg/mL was significantly higher in patients with low serum phosphorus, low Ca × P product, low serum alkaline phosphatase and those older than 65 years.
conclusionLow serum iPTH level is an independent predictor of infection-related mortality in incident dialysis patients.
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