ArticlePloS one2019
Mixotrophic cultivation of Spirulina platensis in dairy wastewater: Effects on the production of biomass, biochemical composition and antioxidant capacity.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Assessing the impact of Spirulina supplementation on the growth of children and adolescents: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Article
- Organic culture of Spirulina: effects of C and N sources on biomass and biomolecules production in linear and helical morphotypes.Folia microbiologica · 2025Article
- Review
- Production and Applications of Cyanobacterial Phycocyanin: Trends and Prospects.Indian journal of microbiology · 2025Article
- Evaluation of Growth Performance, Biochemical Composition, and Polyhydroxyalkanoates Production of Four Cyanobacterial Species Grown in Cheese Whey.Microorganisms · 2025Article
- Use of Enriched Mine Water to Grow the CyanobacteriumFoods (Basel, Switzerland) · 2025Article
- Phycochemistry and pharmacological significance of filamentous cyanobacterium Spirulina sp.Bioresources and bioprocessing · 2025Review
- Mixotrophic Cultivation ofMarine drugs · 2025Article
- Dairy Wastewaters to Promote Mixotrophic Metabolism inLife (Basel, Switzerland) · 2025Article
- Solar bioreactors used for the industrial production of microalgae.Applied microbiology and biotechnology · 2023Review
- Microalgal conversion of whey and lactose containing substrates: current state and challenges.Biodegradation · 2023Review
- Co-Producing Phycocyanin and Bioplastic inBiotech (Basel (Switzerland)) · 2023Article
- Effects of different bicarbonate onFrontiers in bioengineering and biotechnology · 2022Article
- Pyrolysis-GCMS of Spirulina platensis: Evaluation of biomasses cultivated under autotrophic and mixotrophic conditions.PloS one · 2022Article
- Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?Physiological reports · 2021Article
- Variability in Macro- and Micronutrients of 15 Commercially Available Microalgae Powders.Marine drugs · 2021Article
- Development and cost-benefit analysis of a novel process for biofuel production from microalgae using pre-treated high-strength fresh cheese whey wastewater.Environmental science and pollution research international · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mixotrophic cultivation of microalgae provides a very promising alternative for producing carbohydrate-rich biomass to convert into bioethanol and value-added biocompounds, such as vitamins, pigments, proteins, lipids and antioxidant compounds. Spirulina platensis may present high yields of biomass and carbohydrates when it is grown under mixotrophic conditions using cheese whey. However, there are no previous studies evaluating the influence of this culture system on the profile of fatty acids or antioxidant compounds of this species, which are extremely important for food and pharmaceutical applications and would add value to the cultivation process. S. platensis presented higher specific growth rates, biomass productivity and carbohydrate content under mixotrophic conditions; however, the antioxidant capacity and the protein and lipid content were lower than that of the autotrophic culture. The maximum biomass yield was 2.98 ±0.07 g/L in growth medium with 5.0% whey. The phenolic compound concentration was the same for the biomass obtained under autotrophic and mixotrophic conditions with 2.5% and 5.0% whey. The phenolic compound concentrations showed no significant differences except for that in the growth medium with 10.0% whey, which presented an average value of 22.37±0.14 mg gallic acid/g. Mixotrophic cultivation of S. platensis using whey can be considered a viable alternative to reduce the costs of producing S. platensis biomass and carbohydrates, shorten cultivation time and produce carbohydrates, as it does not require adding expensive chemical nutrients to the growth medium and also takes advantage of cheese whey, an adverse dairy industry byproduct.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.