Evidence map›Paper›PMID 31647775›Full record

Trial reportPhotobiomodulation, photomedicine, and laser surgery2019

Transcranial Photobiomodulation with Near-Infrared Light for Generalized Anxiety Disorder: A Pilot Study.

Marco Maiello, Olivia M Losiewicz, Eric Bui, Vincenza Spera, Michael R Hamblin, Luana Marques, Paolo Cassano

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in Photobiomodulation, photomedicine, and laser surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06352372 (Safety and Efficacy of Transcranial Photobiomodulation), which is not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06352372 phase2completednot on this mapstarted 2024, after this paper: background citation

Safety and Efficacy of Transcranial Photobiomodulation (tPBM) for Individuals With Autism Spectrum Disorder and Epileptiform Activity

TypeinterventionalSponsorRichard FryeRan2024 to 2026Enrolled6ConditionsAutism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental DisordersArmsnoninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Marco MaielloDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Olivia M LosiewiczDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Eric BuiDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Vincenza SperaDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts.
Luana MarquesDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Paolo CassanoDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Harvard University · USUniversity of Pisa · IT

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Patient SafetyAdolescentAdultAge FactorsAnxiety DisordersBrainFemaleFollow-Up StudiesHumansInfrared RaysLow-Level Light TherapyMalePilot ProjectsProspective StudiesRisk AssessmentSeverity of Illness Indexgeneralized anxiety disorderLLLTlow-level light therapynear-infraredneuromodulationNIRphotobiomodulationtranscranial

Identifiers

PMID31647775
PMCPMC6818480
OpenAlexW2981784386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.