ArticleHippocampus2020
Cardiorespiratory fitness predicts effective connectivity between the hippocampus and default mode network nodes in young adults.
Article in Hippocampus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Cardiorespiratory fitness, hippocampal subfield volumes, and mnemonic discrimination task performance in aging.Human brain mapping · 2021Trial
- The combination of exercise and psychedelics for the treatment of major depressive disorder.Discover mental health · 2026Article
- Sport-specific demands on sustained attention in elite athletes: a novel within-subjects approach for investigation.Frontiers in sports and active living · 2026Article
- The association between cardiorespiratory fitness and resting-state functional connectivity in adults with Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Vigorous Exercise Enhances Verbal Fluency Performance in Healthy Young Adults.Brain sciences · 2025Article
- Physical Exercise Benefits Cognition: A Narrative Review of Evidence and Possible Mechanisms.Advances in neurobiology · 2025Review
- Trait-level predictors of human performance outcomes in personnel engaged in stressful laboratory and field tasks.Frontiers in psychology · 2024Article
- Cardiorespiratory fitness is associated with cortical thickness of medial temporal brain areas associated with spatial cognition in young but not older adults.The European journal of neuroscience · 2024Article
- Hippocampal Resting State Functional Connectivity Associated with Physical Activity in Periadolescent Children.Brain sciences · 2023Article
- The Interaction Effect of Sleep Deprivation and Treadmill Exercise in Various Durations on Spatial Memory with Respect to the Oxidative Status of Rats.Neurochemical research · 2023Article
- Cardiorespiratory fitness is associated with hippocampal resting state connectivity in women newly diagnosed with breast cancer.Frontiers in cognition · 2023Article
- Brain default mode network mediates the association between negative perfectionism and exercise dependence.Journal of behavioral addictions · 2022Article
- Exploring the Associations between Functional Capacity, Cognitive Function and Well-Being in Older Adults.Life (Basel, Switzerland) · 2022Article
- Cardiorespiratory fitness is associated with fMRI signal in right cerebellum lobule VIIa Crus I and II during spatial navigation in older adult women.Frontiers in aging neuroscience · 2022Article
- Seeing the Forest and Its Trees Together: Implementing 3D Light Microscopy Pipelines for Cell Type Mapping in the Mouse Brain.Frontiers in neuroanatomy · 2021Review
- Poor physical fitness is associated with impaired memory, executive function, and depression in institutionalized older adults: a cross-sectional study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Rodent and human studies examining the relationship between aerobic exercise, brain structure, and brain function indicate that the hippocampus (HC), a brain region critical for episodic memory, demonstrates striking plasticity in response to exercise. Beyond the hippocampal memory system, human studies also indicate that aerobic exercise and cardiorespiratory fitness (CRF) are associated with individual differences in large-scale brain networks responsible for broad cognitive domains. Examining network activity in large-scale resting-state brain networks may provide a link connecting the observed relationships between aerobic exercise, hippocampal plasticity, and cognitive enhancement within broad cognitive domains. Previously, CRF has been associated with increased functional connectivity of the default mode network (DMN), specifically in older adults. However, how CRF relates to the magnitude and directionality of connectivity, or effective connectivity, between the HC and other DMN nodes remains unknown. We used resting-state fMRI and conditional Granger causality analysis (CGCA) to test the hypothesis that CRF positively predicts effective connectivity between the HC and other DMN nodes in healthy young adults. Twenty-six participants (ages 18-35 years) underwent a treadmill test to determine CRF by estimating its primary determinant, maximal oxygen uptake (V
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.