Evidence map›Paper›PMID 31647602›Full record

ArticleMolecular oncology2020

NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin.

Alice H L Bong, Mélanie Robitaille, Michael J G Milevskiy, Sarah J Roberts-Thomson, Gregory R Monteith

Open access · goldAbstract read
In one paragraph

Article in Molecular oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Neuronal calcium sensor 1 (NCS1) dependent modulation of neuronal morphology and development.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alice H L BongSchool of Pharmacy, The University of Queensland, Brisbane, Qld, Australia.ORCID 0000-0003-0790-200X
Mélanie RobitailleSchool of Pharmacy, The University of Queensland, Brisbane, Qld, Australia.
Michael J G MilevskiyACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.
Sarah J Roberts-ThomsonSchool of Pharmacy, The University of Queensland, Brisbane, Qld, Australia.
Gregory R MonteithSchool of Pharmacy, The University of Queensland, Brisbane, Qld, Australia.
The University of Queensland · AUTranslational Research Institute · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal calcium sensor-1 (NCS-1) is a positive modulator of IP

Indexed as

Adenosine TriphosphateAntineoplastic AgentsBreast NeoplasmsCalciumCalcium-Binding ProteinsCalcium ChannelsCalcium SignalingCell DeathCell Line, TumorCell ProliferationDatabases, GeneticDoxorubicinEndoplasmic ReticulumFemaleGene Expression Regulation, NeoplasticGene SilencingAdenosine TriphosphateAntineoplastic AgentsCalciumCalcium-Binding ProteinsCalcium ChannelsDoxorubicinfrequenin calcium sensor proteinsNeuronal Calcium-Sensor ProteinsNeuropeptidesORAI1 ProteinORAI1 protein, humanRNA, Small Interferingbasal breast cancercalciumchemotherapyNCS-1ORAI1

Identifiers

PMID31647602
PMCPMC6944103
OpenAlexW2981954709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.