ArticleAmerican journal of industrial medicine2020
Manganese exposure, parkinsonian signs, and quality of life in South African mine workers.
Article in American journal of industrial medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Impact of Environmental Airborne Manganese Exposure on Cognitive and Motor Functions in Adults: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Neurotoxic Effect of Manganese and Vanadium Co-Exposure in Animal Models of Parkinson's Disease.International journal of molecular sciences · 2026Article
- Utilizing T1-weighted MRI intensity indices to evaluate in-vivo neurotoxicity in a South African cohort with environmental manganese exposure.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025Article
- Career duration and later-life health conditions among former professional American-style football players.Occupational and environmental medicine · 2024Article
- Expression of Manganese Transporters ZIP8, ZIP14, and ZnT10 in Brain Barrier Tissues.International journal of molecular sciences · 2024Article
- Signal Transduction Associated with Mn-induced Neurological Dysfunction.Biological trace element research · 2024Review
- Occupational, environmental, and toxicological health risks of mining metals for lithium-ion batteries: a narrative review of the Pubmed database.Journal of occupational medicine and toxicology (London, England) · 2024Review
- Manganese and Vanadium Co-Exposure Induces Severe Neurotoxicity in the Olfactory System: Relevance to Metal-Induced Parkinsonism.International journal of molecular sciences · 2024Article
- Olfactory tract/bulb metal concentration in Manganese-exposed mineworkers.Neurotoxicology · 2024Article
- Trace Elements in Alzheimer's Disease and Dementia: The Current State of Knowledge.Journal of clinical medicine · 2024Review
- The role of TFEB-mediated autophagy-lysosome dysfunction in manganese neurotoxicity.Current research in toxicology · 2024Article
- Rare Earth and Platinum Group Elements In Sub-Saharan Africa and Global Health: The Dark Side of the Burgeoning of Technology.Environmental health insights · 2024Review
- Transcriptomics-based investigation of manganese dioxide nanoparticle toxicity in rats' choroid plexus.Scientific reports · 2023Article
- Prevalence of Parkinsonism Among Foundry Workers in an Automobile Manufacturing Factory in Tehran.Cureus · 2022Article
- Different components of air pollutants and neurological disorders.Frontiers in public health · 2022Review
- The association of bone and blood manganese with motor function in Chinese workers.Neurotoxicology · 2022Article
- Depression and anxiety in a manganese-exposed community.Neurotoxicology · 2021Article
- Applications and Biological Activity of Nanoparticles of Manganese and Manganese Oxides in In Vitro and In Vivo Models.Nanomaterials (Basel, Switzerland) · 2021Review
- Severity of parkinsonism associated with environmental manganese exposure.Environmental health : a global access science source · 2021Article
- Short Report: Using Targeted Urine Metabolomics to Distinguish Between Manganese Exposed and Unexposed Workers in a Small Occupational Cohort.Frontiers in public health · 2021Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundManganese (Mn) neurotoxicity is associated with parkinsonism; the associated motor deficits can affect individuals' quality of life (QoL). We investigated associations between Mn exposure, parkinsonian signs, and QoL in Mn mine workers.
methodsWe assessed parkinsonian signs and QoL in 187 black South African Mn mine workers, using the Unified Parkinson Disease Rating Scale motor subsection 3 (UPDRS3) and the Parkinson Disease Questionnaire (PDQ-39), respectively. We estimated cumulative Mn exposure in mg Mn/m
resultsParticipants' mean age was 41.8 years (range, 21-67 years); 97.3% were male. Estimated mean cumulative Mn exposure at the time of examination was 5.4 mg Mn/m
conclusionIn this cohort of employed Mn mine workers, parkinsonian signs were common and were associated with both estimated cumulative Mn exposure and poorer QoL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.