ArticleThe international journal of occupational and environmental medicine2020
Effects of Various Densities of 50 Hz Electromagnetic Field on Serum IL-9, IL-10, and TNF-α Levels.
Article in The international journal of occupational and environmental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- LF-EMF Compound Block Type Signal Activates Human Neutrophilic Granulocytes In Vivo.Bioelectromagnetics · 2022Trial
- Extremely low-frequency electromagnetic fields targeting spleen modifies the populations of immunocytes in the spleen.Bioelectromagnetics · 2025Article
- Effect of short-term extremely low-frequency electromagnetic field on respiratory functions.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Effects of Extremely Low-Frequency Electromagnetic Field Treatment on ASD Symptoms in Children: A Pilot Study.Brain sciences · 2024Article
- Review
- ChronicJournal of clinical medicine · 2024Article
- TH1/TH2 Cytokine Profile and Their Relationship with Hematological Parameters in Patients with Acute Limb Ischemia.Reports of biochemistry & molecular biology · 2024Article
- Occupational Exposure to Electromagnetic Fields-Different from General Public Exposure and Laboratory Studies.International journal of environmental research and public health · 2023Article
- System-level biological effects of extremely low-frequency electromagnetic fields: anFrontiers in neuroscience · 2023Review
- A regulatory pathway model of neuropsychological disruption in Havana syndrome.Frontiers in psychiatry · 2023Article
- Open Questions on the Electromagnetic Field Contribution to the Risk of Neurodegenerative Diseases.International journal of environmental research and public health · 2022Review
- Role of insulin/glucagon ratio and cell redox state in the hyperglycaemia induced by exposure to a 60-Hz magnetic field in rats.Scientific reports · 2021Article
- Wound Repair and Extremely Low Frequency-Electromagnetic Field: Insight from In Vitro Study and Potential Clinical Application.International journal of molecular sciences · 2021Review
- Electromagnetic Field (EMF) Radiation Alters Estrogen Release from the Pig Myometrium during the Peri-Implantation Period.International journal of molecular sciences · 2021Article
- Extremely Low-Frequency Magnetic Field as a Stress Factor-Really Detrimental?-Insight into Literature from the Last Decade.Brain sciences · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtremely low-frequency electromagnetic fields (ELF-EMFs) are abundantly produced in modern societies. In recent years, interest in the possible effects of ELF-EMFs on the immune system has progressively increased.
objectiveTo examine the effects of ELF-EMFs with magnetic flux densities of 1, 100, 500, and 2000 μT on the serum levels of interleukin (IL)-9, IL-10, and tumor necrosis factor-alpha (TNF-α).
methods80 adult male rats were exposed to ELF-EMFs at a frequency of 50 Hz for 2 h/day for 60 days. The serum cytokines were measured at two phases of pre- and post-stimulation of the immune system by human serum albumin (HSA).
resultsSerum levels of IL-9 and TNF-α, as pro-inflammatory cytokines, were decreased due to 50 Hz EMFs exposure compared with the controls in the pre- and post-stimulation phases. On the contrary, exposures to 1 and 100 μT 50 Hz EMFs increased the levels of antiinflammatory cytokine, and IL-10 only in the pre-stimulation phase. In the post-stimulation phase, the mean level of serum IL-10 was not changed in the experimental groups.
conclusionThe magnetic flux densities of 1 and 100 μT 50 Hz EMFs had more immunological effects than EMFs with higher densities. Exposure to 50 Hz EMFs may activate anti-inflammatory effects in rats, by down-modulation of pro-inflammatory cytokines (IL-9 and TNF-α) and induction of the anti-inflammatory cytokine (IL-10).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.