Evidence map›Paper›PMID 31647050›Full record

ArticleEpidemiology and infection2019

Updated modelling of the prevalence of immunodeficiency-associated long-term vaccine-derived poliovirus (iVDPV) excreters.

D A Kalkowska, M A Pallansch, K M Thompson

Abstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Worst-case scenarios: Modeling uncontrolled type 2 polio transmission.Risk analysis : an official publication of the Society for Risk Analysis · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Global Transmission of Live Polioviruses: Updated Dynamic Modeling of the Polio Endgame.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  12. A Health Economic Analysis for Oral Poliovirus Vaccine to Prevent COVID-19 in the United States.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Review
  13. Potential Future Use, Costs, and Value of Poliovirus Vaccines.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  14. Article
  15. Review
  16. Health Economic Analysis of Antiviral Drugs in the Global Polio Eradication Endgame.Medical decision making : an international journal of the Society for Medical Decision Making
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D A KalkowskaKid Risk, Inc., Orlando, USA.
M A PallanschDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
K M ThompsonKid Risk, Inc., Orlando, USA.ORCID 0000-0002-0849-9147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conditions and evidence continue to evolve related to the prediction of the prevalence of immunodeficiency-associated long-term vaccine-derived poliovirus (iVDPV) excreters, which affect assumptions related to forecasting risks and evaluating potential risk management options. Multiple recent reviews provided information about individual iVDPV excreters, but inconsistencies among the reviews raise some challenges. This analysis revisits the available evidence related to iVDPV excreters and provides updated model estimates that can support future risk management decisions. The results suggest that the prevalence of iVDPV excreters remains highly uncertain and variable, but generally confirms the importance of managing the risks associated with iVDPV excreters throughout the polio endgame in the context of successful cessation of all oral poliovirus vaccine use.

Indexed as

Poliovirus VaccinesVirus SheddingAntiviral AgentsFemaleGlobal HealthHumansImmunoglobulins, IntravenousImmunologic Deficiency SyndromesImmunologic FactorsMaleModels, ImmunologicalPoliomyelitisPrevalencePublic Health SurveillanceRisk AssessmentAntiviral AgentsImmunoglobulins, IntravenousImmunologic FactorsPoliovirus VaccinesPoliopolio vaccine virusvirology (human) and epidemiology

Identifiers

PMID31647050
PMCPMC6813650

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.