Evidence map›Paper›PMID 31646939›Full record

ArticleMolecular pain

NPY2R signaling gates spontaneous and mechanical, but not thermal, pain transmission.

Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu

Abstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A neuropeptide code for itch.Nature reviews. Neuroscience · 2021
    Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sihan ChenDepartment of Anesthesiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China.
Xian-Yu LiuCenter for the Study of Itch, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-6089-8826
Yingfu JiaoDepartment of Anesthesiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China.
Zhou-Feng ChenCenter for the Study of Itch, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-6859-7910
Weifeng YuDepartment of Anesthesiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China.

Funding

MOLECULAR MECHANISMS OF THE ITCH SENSATION IN THE SPINAL CORDR01AR056318 · NIAMS · WASHINGTON UNIVERSITY · PI CHEN, ZHOUFENG · 2009 to 2018
$4.5M
MECHANISMS OF DESENSITIZATION OF MOR1D-GRPR CROSSTALKR01DA037261 · NIDA · WASHINGTON UNIVERSITY · PI CHEN, ZHOUFENG · 2015 to 2019
$2.1M
UNDERSTANDING MECHANISMS THAT BLOCK GRPR-MEDIATED CHRONIC ITCHR01NS094344 · NINDS · WASHINGTON UNIVERSITY · PI CHEN, ZHOUFENG · 2015 to 2019
$1.8M
NIAMS NIH HHS R01 AR056318NIDA NIH HHS R01 DA037261NINDS NIH HHS R01 NS094344
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArginineBenzazepinesInjections, SpinalMaleMiceMice, Inbred C57BLPainReceptors, Neuropeptide YSpinal CordArginineBenzazepinesBIBO 3304BIIE 0246neuropeptide Y2 receptorReceptors, Neuropeptide YNPYpainspinal cordY1RY2R

Identifiers

PMID31646939
PMCPMC6880052

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.