Evidence map›Paper›PMID 31646256›Full record

ArticleInternational journal of reproductive biomedicine2019

Niacin improves maturation and cryo-tolerance of bovine in vitro matured oocytes: An experimental study.

Mojtaba Kafi, Mahboobeh Ashrafi, Mehdi Azari, Borhan Jandarroodi, Beheshteh Abouhamzeh, Arash Rakhshi Asl

Open access · goldAbstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Food science & nutrition · 2025
    Article
  5. Article
  6. Article
  7. A Molecular Perspective and Role of NADInternational journal of molecular sciences · 2024
    Review
  8. Can Nicotinamide Adenine Dinucleotide (NADAnimals : an open access journal from MDPI · 2024
    Review
  9. New strategies for germ cell cryopreservation: Cryoinjury modulation.Clinical and experimental reproductive medicine · 2023
    Article
  10. Article
  11. NADThe Journal of reproduction and development · 2022
    Review
  12. Insights into the NADThe Journal of reproduction and development · 2022
    Article
  13. Supplemental Nicotinic Acid Elevates NADAnimals : an open access journal from MDPI · 2022
    Article
  14. Article
  15. Supplementing media with NADThe Journal of reproduction and development · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mojtaba KafiDepartment of Animal Reproduction, School of Veterinary Medicine, Shiraz University Shiraz Iran.
Mahboobeh AshrafiDepartment of Basic Sciences, School of Veterinary Medicine, Shiraz University Shiraz Iran.
Mehdi AzariDepartment of Animal Reproduction, School of Veterinary Medicine, Shiraz University Shiraz Iran.
Borhan JandarroodiDepartment of Animal Reproduction, School of Veterinary Medicine, Shiraz University Shiraz Iran.
Beheshteh AbouhamzehDepartment of Anatomical Sciences, School of Medicine, AJA University of Medical Sciences Tehran Iran.
Arash Rakhshi AslDepartment of Basic Sciences, School of Veterinary Medicine, Shiraz University Shiraz Iran.
Shiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNicotinic acid (niacin) is a broad-spectrum lipid-modifying agent that has potent antioxidant properties and reduces the production of lipid peroxidation.

objectiveThe purpose of the present study was to investigate the maturation, embryo development and cryo-tolerance merit, and levels of malondialdehyde (MDA), total oxidant status, and total antioxidant capacity following the supplementation of bovine oocytes maturation medium with different concentrations of niacin. MATERIALS AND

methodsImmature cumulus-oocyte complexes were cultured in tissue culture medium-199 maturation media supplemented with 0, 100, 200, and 400

resultsThe results indicated that although the treatment with 400

conclusionNiacin could improve the quality of in vitro embryo production (IVP) embryos and tolerance of bovine oocytes to vitrification.

Indexed as

BovineEmbryonic developmentNiacin, OocytesVitrification

Identifiers

PMID31646256
PMCPMC6804331
OpenAlexW2976282286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.