Evidence map›Paper›PMID 31646200›Full record

ArticleBMJ paediatrics open2019

Association of faecal pH with childhood stunting: Results from a cross-sectional study.

Md Shabab Hossain, Subhasish Das, Md Amran Gazi, Md Ashraful Alam, Nur Muhammad Shahedul Haque, Mustafa Mahfuz, Tahmeed Ahmed, Chris J Damman

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in BMJ paediatrics open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02812615 (Stunting and Bangladesh Environmental Enteric Dysfunction Study), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02812615 naunknown statusnot on this map

Stunting and Bangladesh Environmental Enteric Dysfunction Study

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2016 to 2022Enrolled1,575ConditionsMalnutrition, InfectionArmsEgg, Milk, Albendazole/Pyrantel Pamoate, Nutritional counselling, Micronutrient sprinkles
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Neonatal faecal abundance ofGut microbiome (Cambridge, England) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Md Shabab HossainNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.ORCID 0000-0002-2862-8639
Subhasish DasNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Md Amran GaziNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Md Ashraful AlamNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Nur Muhammad Shahedul HaqueNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Mustafa MahfuzNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Tahmeed AhmedNutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Chris J DammanDivision of Gastroenterology, University of Washington, Seattle, Washington, USA.
International Centre for Diarrhoeal Disease Research · BDGates Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGut microbiota plays an important role in the growth of children. The gut of children with optimum growth is enriched in certain species, especially

methodsIn this cross-sectional study, 100 children with length-for-age Z score (LAZ) <-1 aged between 12 and 18 months were enrolled from the ongoing Bangladesh Environmental Enteric Dysfunction study conducted in Dhaka, Bangladesh. LAZ was measured by anthropometry and data on factors affecting linear growth were recorded. Faecal pH measurement was done using pH metre on freshly collected non-diarrhoeal faecal samples following standard procedure. Multiple quantile regression was done to quantify the relation between faecal pH and LAZ scores.

resultsThe mean LAZ and faecal pH of the children were -2.12±0.80 and 5.84±1.11, respectively. Pearson correlation analysis showed a statistically significant negative correlation between stool pH and the LAZ scores (p<0.01). After inclusion of other factors affecting linear growth into the regression model, a statistically significant inverse association was observed between faecal pH and LAZ score (p<0.01).

conclusionElevated faecal pH was found to have a significant association with stunted growth. As an indicator of gut microbiota status, faecal pH might have emerged as a possible indirect determinant of childhood stunting. TRIAL REGISTRATION NUMBER: NCT02812615.

Indexed as

BangladeshchildrenFaecal pHgrowth

Identifiers

PMID31646200
PMCPMC6782033
OpenAlexW2972910060

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.