Evidence map›Paper›PMID 31646144›Full record

ArticleGerms2019

Characteristics of influenza in elderly patients with and without diabetes, hospitalized for severe acute respiratory infection in a tertiary care hospital from Bucharest Romania - a three-year prospective epidemiological surveillance study.

Daniela Pițigoi, Maria Nițescu, Anca Streinu-Cercel, Rodica Bacruban, Alina Elena Ivanciuc, Mihaela Lazăr, Carmen Maria Cherciu, Maria Dorina Crăciun, Victoria Aramă, Adrian Streinu-Cercel and 1 more

Abstract read
In one paragraph

Article in Germs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniela PițigoiMD, PhD, Associate Professor, Department of Epidemiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.
Maria NițescuMD, PhD, Associate Professor, Department of Hygiene and Medical Ecology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.
Anca Streinu-CercelMD, PhD, Associate Professor, Department of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.
Rodica BacrubanMD, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.
Alina Elena IvanciucBiologist, PhD student, National Institute for Medico-Military Research Cantacuzino, National Influenza Centre, No. 103 Splaiul Independenței, Bucharest 050096, Romania.
Mihaela LazărBiologist, PhD, National Institute for Medico-Military Research Cantacuzino, National Influenza Centre, No. 103 Splaiul Independenței, Bucharest 050096, Romania.
Carmen Maria CherciuBiochemist, National Institute for Medico-Military Research Cantacuzino, National Influenza Centre, No. 103 Splaiul Independenței, Bucharest 050096, Romania.
Maria Dorina CrăciunMD, PhD, Assistant Lecturer, Department of Epidemiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Grigore Alexandrescu Clinical Children's Emergency Hospital, No. 30-32 Iancu de Hunedoara boulevard, Bucharest 011743, Romania.
Victoria AramăMD, PhD, Professor, Department of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.
Adrian Streinu-CercelMD, PhD, Professor, Department of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.
Oana SăndulescuMD, PhD, Associate Professor, Department of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", No. 1 Dr. Calistrat Grozovici street, Bucharest 021105, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with diabetes may be at a higher risk of developing complicated influenza. We report the characteristics of influenza in hospitalized elderly patients with and without diabetes, in three consecutive influenza seasons.

methodsThe study included patients admitted for severe acute respiratory infection (SARI) in the National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, during a three-year active epidemiological surveillance study (2015/16, 2016/17, 2017/18), in the I-MOVE+ hospital network.

resultsA total of 349 patients were tested by PCR over the duration of the study. The percentage of patients with diabetes was comparable throughout the seasons: 34.7%, 28.3% and 30.4% (p=0.587). Influenza A was the main viral type circulating in 2015/16 and 2016/17 (100% and 97.6%) in our study population, while in 2017/18, B viruses predominated (90.0%). Diabetics presented a higher median number of comorbidities (3 vs. 2) p<0.001, and two-fold higher odds of also associating obesity (OR=2.1, 95%CI:1.3-3.4, p=0.003), compared to those without diabetes. Diabetics also tested positive for influenza more often (p=0.296). Only 6 patients with diabetes (5.4%) from our study had been vaccinated against influenza, and most (n=4) of those who had been vaccinated tested negative for influenza.

conclusionsOur study is the first to describe the circulation of influenza viral types in elderly diabetic patients hospitalized for SARI. The results reinforce the national and international recommendation to vaccinate against influenza all patients with diabetes.

Indexed as

comorbiditiesdiabeteselderly patientsInfluenzaviral types

Identifiers

PMID31646144
PMCPMC6783639

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.