Evidence map›Paper›PMID 31646081›Full record

ArticleOncoimmunology

Irreversible electroporation of locally advanced pancreatic cancer transiently alleviates immune suppression and creates a window for antitumor T cell activation.

Hester J Scheffer, Anita G M Stam, Bart Geboers, Laurien G P H Vroomen, Alette Ruarus, Beaunelle de Bruijn, M Petrousjka van den Tol, Geert Kazemier, Martijn R Meijerink, Tanja D de Gruijl

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.

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  20. Prospects of Synergy: Local Interventions and CAR T Cell Therapy in Solid Tumors.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hester J SchefferDepartments of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Anita G M StamDepartments of Medical Oncology, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Bart GeboersDepartments of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-8137-9299
Laurien G P H VroomenDepartments of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Alette RuarusDepartments of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Beaunelle de BruijnDepartments of Medical Oncology, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
M Petrousjka van den TolDepartments of Surgery, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Geert KazemierDepartments of Surgery, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Martijn R MeijerinkDepartments of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.
Tanja D de GruijlDepartments of Medical Oncology, Amsterdam University Medical Center, Vrije Universiteit-Cancer Center Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-1464-8978
Amsterdam University Medical Centers · NLCancer Center Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Irreversible electroporationlocally advanced pancreatic cancerPD-1T cellsTregWT1

Identifiers

PMID31646081
PMCPMC6791414
OpenAlexW2970678812

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.