Evidence map›Paper›PMID 31646056›Full record

ArticleBiomedical optics express2019

Simultaneous label-free autofluorescence and multi-harmonic imaging reveals

Jang Hyuk Lee, Jose J Rico-Jimenez, Chi Zhang, Aneesh Alex, Eric J Chaney, Ronit Barkalifa, Darold R Spillman, Marina Marjanovic, Zane Arp, Steve R Hood and 1 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Detecting drug-induced nephrotoxicity using simultaneous label-free autofluorescence multiharmonic microscopy.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  2. Article
  3. Artificial Intelligence in Label-Free Optical Imaging Applications.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy.Journal of visualized experiments : JoVE · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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  17. Nonlinear Imaging Histopathology: A Pipeline to Correlate Gold-Standard Hematoxylin and Eosin Staining With Modern Nonlinear Microscopy.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jang Hyuk LeeCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jose J Rico-JimenezCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID https://orcid.org/0000-0003-4022-3228
Chi ZhangCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Aneesh AlexGlaxoSmithKline, Collegeville, PA 19426, USA.
Eric J ChaneyCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Ronit BarkalifaCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Darold R SpillmanCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID https://orcid.org/0000-0001-9946-2659
Marina MarjanovicCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Zane ArpGlaxoSmithKline, Collegeville, PA 19426, USA.
Steve R HoodGlaxoSmithKline, Stevenage, UK.
Stephen A BoppartCenter for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID https://orcid.org/0000-0002-9386-5630

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simultaneous quantification of multifarious cellular metabolites and the extracellular matrix

Identifiers

PMID31646056
PMCPMC6788598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.