Evidence map›Paper›PMID 31646055›Full record

ArticleBiomedical optics express2019

Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging.

Zhongyu Liu, Stephen Mackay, Dylan M Gordon, Justin D Anderson, Dustin W Haithcock, Charles J Garson, Guillermo J Tearney, George M Solomon, Kapil Pant, Balabhaskar Prabhakarpandian and 2 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The Development of 3D Primary Co-Culture Models of the Human Airway.International journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. On the path to predicting immune responses in the lung: Modeling the pulmonary innate immune system at the air-liquid interface (ALI).European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Mechanical Stimulation: A Crucial Element of Organ-on-Chip Models.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhongyu LiuDepartment of Pediatrics, University of Alabama at Birmingham, Lowder Building Suite 620, 1600 7th Avenue South, Birmingham, AL 35233, USA.
Stephen MackayDepartment of Pediatrics, University of Alabama at Birmingham, Lowder Building Suite 620, 1600 7th Avenue South, Birmingham, AL 35233, USA.
Dylan M GordonBiomedical Technology, CFD Research Corporation, 701 McMillian Way NW, Huntsville, AL 35806, USA.
Justin D AndersonDepartment of Pediatrics, University of Alabama at Birmingham, Lowder Building Suite 620, 1600 7th Avenue South, Birmingham, AL 35233, USA.
Dustin W HaithcockBiomedical Technology, CFD Research Corporation, 701 McMillian Way NW, Huntsville, AL 35806, USA.
Charles J GarsonBiomedical Technology, CFD Research Corporation, 701 McMillian Way NW, Huntsville, AL 35806, USA.
Guillermo J TearneyDepartment of Pathology, Wellman Center for Photomedicine, Massachusetts General Hospital, & Harvard Medical School, 55 Fruit St., Boston, MA 02114, USA.
George M SolomonGregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, MCLM 706, 1918 University Blvd, Birmingham, AL 35294, USA.
Kapil PantBiomedical Technology, CFD Research Corporation, 701 McMillian Way NW, Huntsville, AL 35806, USA.
Balabhaskar PrabhakarpandianBiomedical Technology, CFD Research Corporation, 701 McMillian Way NW, Huntsville, AL 35806, USA.
Steven M RoweDepartment of Pediatrics, University of Alabama at Birmingham, Lowder Building Suite 620, 1600 7th Avenue South, Birmingham, AL 35233, USA.
Jennifer S GuimbellotDepartment of Pediatrics, University of Alabama at Birmingham, Lowder Building Suite 620, 1600 7th Avenue South, Birmingham, AL 35233, USA.

Funding

UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Susan Elizabeth Birket · 2007 to 2026
$23.0M
Translational Program in CFTR-Related Airway DiseasesR35HL135816 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROWE, STEVEN MARK · 2017 to 2022
$6.3M
Functional Categorization of Ciliary Motion in PCDK08HL138153 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SOLOMON, GEORGE MARTIN · 2019 to 2023
$799k
NCATS NIH HHS UL1 TR001417NHLBI NIH HHS K08 HL138153NHLBI NIH HHS R35 HL135816NIDDK NIH HHS P30 DK072482
6 · The paper itself

Abstract

We have developed a human bronchial epithelial (HBE) cell and endothelial cell co-cultured microfluidic model to mimic the

Identifiers

PMID31646055
PMCPMC6788592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.