Evidence map›Paper›PMID 31646040›Full record

ArticleBiomedical optics express2019

Optical properties of brain tissues at the different stages of glioma development in rats: pilot study.

Elina A Genina, Alexey N Bashkatov, Daria K Tuchina, Polina A Dyachenko Timoshina, Nikita Navolokin, Alexander Shirokov, Alexander Khorovodov, Andrey Terskov, Maria Klimova, Aysel Mamedova and 5 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Chemigenetic Far-Red Labels and CaJournal of the American Chemical Society · 2024
    Article
  8. Article
  9. Avoiding bias in fluorescence sensor readout.Nature reviews. Neuroscience · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Real-time and accurate estimationBiomedical optics express · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Quantitative analysis of the optogenetic excitability of CA1 neurons.Frontiers in computational neuroscience · 2023
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Elina A GeninaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0002-1223-1100
Alexey N BashkatovSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0003-2035-5266
Daria K TuchinaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0003-0203-4979
Polina A Dyachenko TimoshinaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0003-4856-9522
Nikita NavolokinSaratov State Medical University, 112, B. Kazachya str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0001-7876-9758
Alexander ShirokovInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, IBPPM RAS, 13 Prospekt Entuziastov, Saratov 410049, Russia.
Alexander KhorovodovSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.
Andrey TerskovSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.
Maria KlimovaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.
Aysel MamedovaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.
Inna BlokhinaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.
Ilana AgranovichSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0002-7903-3897
Ekaterina ZinchenkoSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0001-7926-1681
Oxana V Semyachkina-GlushkovskayaSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.
Valery V TuchinSaratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0001-7479-2694
Saratov State University · RUInstitute of Biochemistry and Physiology of Plants and Microorganisms · RUSaratov State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, measurements of the optical properties (diffuse reflectance, total and collimated transmittance) of brain tissues in healthy rats and rats with C6-glioma were performed in the spectral range from 350 to 1800 nm. Using these measurements, characteristic tissue optical parameters, such as absorption coefficient, scattering coefficient, reduced scattering coefficient, and scattering anisotropy factor were reconstructed. It was obtained that the 10-day development of glioma led to increase of absorption coefficient, which was associated with the water content elevation in the tumor. However, further development of the tumor (formation of the necrotic core) led to decrease in the water content. The dependence of the scattering properties on the different stages of model glioma development was more complex. Light penetration depth into the healthy and tumor brain was evaluated.

Identifiers

PMID31646040
PMCPMC6788608
OpenAlexW2973940420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.