ArticleHorticulture research2019
Genome-wide association studies in apple reveal loci of large effect controlling apple polyphenols.
Article in Horticulture research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 71 citations in OpenAlex.
- Evaluation of Total Phenols, Flavonoids, and Antioxidant Activity in the Peel and Flesh of Old Apple Cultivars.Foods (Basel, Switzerland) · 2026Article
- Article
- Beyond a simple oxidation reaction: the complex molecular network regulating fruit and vegetable browning.Horticulture research · 2026Article
- Multi-locus GWAS uncovers favorable alleles and candidate genes underlying water stress response in chrysanthemum.BMC plant biology · 2026Article
- On the genetic origins of phenotypes in genome-wide association studies: the SAFE-hBMC bioinformatics · 2026Article
- A bittersweet symphony: genetic insights into cider apple fruit quality.G3 (Bethesda, Md.) · 2026Article
- The Biologically Active Compounds in Fruits of Cultivated Varieties and Wild Species of Apples.Molecules (Basel, Switzerland) · 2025Review
- Untargeted metabolomic genome-wide association study reveals genetic and biochemical insights into polyphenols of apple fruit.Horticulture research · 2025Article
- Integrative analysis of genome-wide association studies of polyphenols in apple fruits identifies the MdDof2.4Horticulture research · 2025Article
- Evaluation of genomic and phenomic prediction for application in apple breeding.BMC plant biology · 2025Article
- Metabolomics Analysis of Phenolic Composition and Content in Five Pear Cultivars Leaves.Plants (Basel, Switzerland) · 2024Article
- Tracing the color: quantitative trait loci analysis reveals new insights into red-flesh pigmentation in apple (Horticulture research · 2024Article
- Genetic architecture and genomic prediction of plant height-related traits in chrysanthemum.Horticulture research · 2024Article
- High-density genetic map and quantitative trait loci map of skin color in hawthorn (Frontiers in genetics · 2024Article
- Comprehensive genetic diversity and genome-wide association studies revealed the genetic basis of avocado fruit quality traits.Frontiers in plant science · 2024Article
- Exploring genetic diversity and ascertaining genetic loci associated with important fruit quality traits in apple (Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Genomewide selection for fruit quality traits in apple: breeding insights gained from prediction and postdiction.Horticulture research · 2023Article
- Population Structure and Association Mapping for Agronomical and Biochemical Traits of a Large Spanish Apple Germplasm.Plants (Basel, Switzerland) · 2023Article
- A multi-locus genome-wide association study reveals the genetics underlying muscadine antioxidant in berry skin.Frontiers in plant science · 2022Article
- Research Progress on Genetic Basis of Fruit Quality Traits in Apple (Frontiers in plant science · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apples are a nutritious food source with significant amounts of polyphenols that contribute to human health and wellbeing, primarily as dietary antioxidants. Although numerous pre- and post-harvest factors can affect the composition of polyphenols in apples, genetics is presumed to play a major role because polyphenol concentration varies dramatically among apple cultivars. Here we investigated the genetic architecture of apple polyphenols by combining high performance liquid chromatography (HPLC) data with ~100,000 single nucleotide polymorphisms (SNPs) from two diverse apple populations. We found that polyphenols can vary in concentration by up to two orders of magnitude across cultivars, and that this dramatic variation was often predictable using genetic markers and frequently controlled by a small number of large effect genetic loci. Using GWAS, we identified candidate genes for the production of quercitrin, epicatechin, catechin, chlorogenic acid, 4-
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.