Evidence map›Paper›PMID 31645729›Full record

ArticleNature2019

Bacterial biodiversity drives the evolution of CRISPR-based phage resistance.

Ellinor O Alseth, Elizabeth Pursey, Adela M Luján, Isobel McLeod, Clare Rollie, Edze R Westra

Open access · greenAbstract read
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 136 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Engineering broad-spectrum phage-resistantApplied and environmental microbiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Phage defence-system abundances vary across environments and increase with viral density.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  13. Abiotic environmental conditions determine phage resistance outcomes in a salt-marsh bacterium.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  14. Complementary killing activities ofAntimicrobial agents and chemotherapy · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ellinor O AlsethEnvironment and Sustainability Institute, Biosciences, University of Exeter, Penryn Campus, Penryn, UK. eao210@exeter.ac.uk.
Elizabeth PurseyEnvironment and Sustainability Institute, Biosciences, University of Exeter, Penryn Campus, Penryn, UK.
Adela M LujánIRNASUS, CONICET, Facultad de Ciencias Químicas, Universidad Católica de Córdoba, Córdoba, Argentina.
Isobel McLeodEnvironment and Sustainability Institute, Biosciences, University of Exeter, Penryn Campus, Penryn, UK.
Clare RollieEnvironment and Sustainability Institute, Biosciences, University of Exeter, Penryn Campus, Penryn, UK.
Edze R WestraEnvironment and Sustainability Institute, Biosciences, University of Exeter, Penryn Campus, Penryn, UK. e.r.westra@exeter.ac.uk.
University of Exeter · GBConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

European Research Council 714478
6 · The paper itself

Abstract

About half of all bacteria carry genes for CRISPR-Cas adaptive immune systems

Indexed as

BiodiversityEvolution, MolecularBacteriophagesCRISPR-Cas SystemsPseudomonas aeruginosaReceptors, VirusReceptors, Virus

Identifiers

PMID31645729
PMCPMC6837874
OpenAlexW2981670863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.