ArticleInternal medicine (Tokyo, Japan)2020
Japanese Spotted Fever with Hemophagocytic Lymphohistiocytosis.
Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Sequential Onset of Japanese Spotted Fever in a Parent-Child Household: A Familial Cluster of Two Cases.Cureus · 2026Article
- Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome.Advances in experimental medicine and biology · 2024Review
- A Case of Critical Japanese Spotted Fever in Zhejiang, China.Infection and drug resistance · 2023Article
- Article
- A Case of Hemophagocytic Lymphohistiocytosis Associated With Mediterranean Spotted Fever in a Healthy 29-Year-Old Female.Open forum infectious diseases · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
Japanese spotted fever (JSF) is an uncommon but potentially fatal infection transmitted by tick bites. We herein report a fulminant case of JSF infection that occurred in an immunocompetent adult that was complicated by disseminated intravascular coagulation and hemophagocytic lymphohistiocytosis (HLH). We discuss the difficulty in making the diagnosis and identifying the complication of HLH in our patient. HLH is a rare complication of rickettsiosis, and this is the first reported case in English of JSF complicated by HLH in an immunocompetent adult. Secondary HLH caused by rickettsiosis requires a different treatment from primary HLH. Rickettsiosis must therefore be considered in patients with HLH.
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