Evidence map›Paper›PMID 31645344›Full record

ArticleCold Spring Harbor molecular case studies2019

Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor.

Lauren M Sanders, Arun Rangaswami, Isabel Bjork, Du Linh Lam, Holly C Beale, Ellen Towle Kephart, Ann Durbin, Katrina Learned, Rob Currie, A Geoffrey Lyle and 14 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. An Overview of Advances in Rare Cancer Diagnosis and Treatment.International journal of molecular sciences · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 3 institutions in 1 country.

Lauren M SandersDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Arun RangaswamiStanford University School of Medicine and Stanford Cancer Institute, Stanford, California 94305, USA.
Isabel BjorkDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Du Linh LamDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Holly C BealeDepartment of Molecular, Cell and Developmental Biology, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Ellen Towle KephartDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Ann DurbinDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Katrina LearnedDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Rob CurrieDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
A Geoffrey LyleDepartment of Molecular, Cell and Developmental Biology, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Jacob PfeilDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Avanthi Tayi ShahDepartment of Pediatrics, Division of Hematology and Oncology, University of California San Francisco, San Francisco, California 94143, USA.
Alex G LeeDepartment of Pediatrics, Division of Hematology and Oncology, University of California San Francisco, San Francisco, California 94143, USA.
Stanley G LeungDepartment of Pediatrics, Division of Hematology and Oncology, University of California San Francisco, San Francisco, California 94143, USA.
Inge H BehroozfardDepartment of Pediatrics, Division of Hematology and Oncology, University of California San Francisco, San Francisco, California 94143, USA.
Marcus R BreeseDepartment of Pediatrics, Division of Hematology and Oncology, University of California San Francisco, San Francisco, California 94143, USA.
Jennifer PeralezStanford University School of Medicine and Stanford Cancer Institute, Stanford, California 94305, USA.
Florette K HazardStanford University School of Medicine and Stanford Cancer Institute, Stanford, California 94305, USA.
Norman LacayoStanford University School of Medicine and Stanford Cancer Institute, Stanford, California 94305, USA.
Sheri L SpuntStanford University School of Medicine and Stanford Cancer Institute, Stanford, California 94305, USA.
David HausslerDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
Sofie R SalamaDepartment of Biomolecular Engineering, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
E Alejandro Sweet-CorderoDepartment of Pediatrics, Division of Hematology and Oncology, University of California San Francisco, San Francisco, California 94143, USA.
Olena M VaskeDepartment of Molecular, Cell and Developmental Biology, UC Santa Cruz Genomics Institute, Santa Cruz, California 95064, USA.
University of California, Santa Cruz · USUniversity of California, San Francisco · USStanford University · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Melinda L. Telli · 2007 to 2026
$71.4M
Howard Hughes Medical InstituteNCI NIH HHS P30 CA124435
6 · The paper itself

Abstract

Gliomatosis peritonei is a rare pathologic finding that is associated with ovarian teratomas and malignant mixed germ cell tumors. The occurrence of gliomatosis as a mature glial implant can impart an improved prognosis to patients with immature ovarian teratoma, making prompt and accurate diagnosis important. We describe a case of recurrent immature teratoma in a 10-yr-old female patient, in which comparative analysis of the RNA sequencing gene expression data from the patient's tumor was used effectively to aid in the diagnosis of gliomatosis peritonei.

Indexed as

Base SequenceChildExome SequencingFemaleGliomaHumansOvarian NeoplasmsPeritoneal NeoplasmsPrognosisRare DiseasesRNA-SeqSequence Analysis, RNATeratomaneoplasm of the nervous system

Identifiers

PMID31645344
PMCPMC6824255
OpenAlexW2982102538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.