Evidence map›Paper›PMID 31645228›Full record

ArticleCNS spectrums2020

Compulsivity is measurable across distinct psychiatric symptom domains and is associated with familial risk and reward-related attentional capture.

Lucy Albertella, Samuel R Chamberlain, Mike E Le Pelley, Lisa-Marie Greenwood, Rico Sc Lee, Lauren Den Ouden, Rebecca A Segrave, Jon E Grant, Murat Yücel

Abstract read
In one paragraph

Article in CNS spectrums, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  5. Implementations of sign- and goal-tracking behavior in humans: A scoping review.Cognitive, affective & behavioral neuroscience · 2025
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  19. Article
  20. The past, present, and future of selection history.Neuroscience and biobehavioral reviews · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucy AlbertellaSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-5232-6414
Samuel R ChamberlainDepartment of Psychiatry, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-7014-8121
Mike E Le PelleySchool of Psychology, UNSW Sydney, New South Wales, Australia.ORCID 0000-0002-5145-5502
Lisa-Marie GreenwoodSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Rico Sc LeeSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Lauren Den OudenSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Rebecca A SegraveSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Jon E Grant *Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA.
Murat Yücel *School of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.

Funding

Wellcome Trust 110049
6 · The paper itself

Abstract

backgroundCompulsivity can be seen across various mental health conditions and refers to a tendency toward repetitive habitual acts that are persistent and functionally impairing. Compulsivity involves dysfunctional reward-related circuitry and is thought to be significantly heritable. Despite this, its measurement from a transdiagnostic perspective has received only scant research attention. Here we examine both the psychometric properties of a recently developed compulsivity scale, as well as its relationship with compulsive symptoms, familial risk, and reward-related attentional capture.

methodsTwo-hundred and sixty individuals participated in the study (mean age = 36.0 [SD = 10.8] years; 60.0% male) and completed the Cambridge-Chicago Compulsivity Trait Scale (CHI-T), along with measures of psychiatric symptoms and family history thereof. Participants also completed a task designed to measure reward-related attentional capture (n = 177).

resultsCHI-T total scores had a normal distribution and acceptable Cronbach's alpha (0.84). CHI-T total scores correlated significantly and positively (all p < 0.05, Bonferroni corrected) with Problematic Usage of the Internet, disordered gambling, obsessive-compulsive symptoms, alcohol misuse, and disordered eating. The scale was correlated significantly with history of addiction and obsessive-compulsive related disorders in first-degree relatives of participants and greater reward-related attentional capture.

conclusionsThese findings suggest that the CHI-T is suitable for use in online studies and constitutes a transdiagnostic marker for a range of compulsive symptoms, their familial loading, and related cognitive markers. Future work should more extensively investigate the scale in normative and clinical cohorts, and the role of value-modulated attentional capture across compulsive disorders.

Indexed as

AttentionGenetic Predisposition to DiseaseRewardAdultCompulsive BehaviorFemaleHumansMaleMedical History TakingPsychometricsAddictioncognition.compulsivemarkerphenotype

Identifiers

PMID31645228
PMCPMC7115959

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.