Evidence map›Paper›PMID 31645218›Full record

SynthesisPathogens and global health2019

Seroprevalence of herpes simplex virus types 1 and 2 in Nigeria: a systematic review and meta-analyses.

Eleazar E Reward, Sophia O Muo, Ibuchukwu N A Orabueze, Anthony C Ike

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pathogens and global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eleazar E RewardDepartment of Microbiology, University of Nigeria, Nsukka, Nigeria.
Sophia O MuoDepartment of Microbiology, University of Nigeria, Nsukka, Nigeria.ORCID 0000-0002-4954-1081
Ibuchukwu N A OrabuezeDepartment of Medical Microbiology, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria.
Anthony C IkeDepartment of Microbiology, University of Nigeria, Nsukka, Nigeria.ORCID 0000-0003-2706-6141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A source of comprehensive information on the prevalence of herpes simplex virus type 1 and 2 (HSV-1 and HSV-2) can help researchers and policymakers address HSV related burden in the society. At the moment, this is not readily available. This study aims to fill this gap by attempting to estimate the seroprevalence of HSV-1 and HSV-2 infections in Nigeria on the basis of published data. A systematic review and meta-analysis including cross-sectional studies on HSV-1 and HSV-2 in Nigeria was conducted. Electronic databases including PubMed/MEDLINE, CENTRAL, African Journals Online (AJOL), ScienceDirect, WHO-Afro Library, WHO-IRIS and African Index Medicus were searched for English Language publications on HSV-1 and HSV-2. Seven relevant publications were identified. Seroprevalence measures of 3 and 23 for HSV-1 and HSV-2, respectively, were extracted. The pooled mean seroprevalences for HSV-1 and HSV-2 were 74.0% (37.4-99.4%) and 63.4% (56.1-70.4%) respectively. The mean seroprevalence of HSV-1 was higher among females, 82.4% (n = 509, CI, 36.6-100.0%), than males, 54.5% (n = 198, CI, 47.6-61.4%). The mean seroprevalence of HSV-2 were 51.8% (n = 1414, CI: 39.4-64.0%) and 86.5% (n = 162, CI: 80.8-91.3%) among healthy and clinical populations, respectively. The study was limited by the paucity of quality studies, variations in diagnostic methods and high heterogeneity in seroprevalence estimates. In conclusion, the seroprevalence of HSV-1 and HSV-2 remain high in Nigeria. Large and representative national epidemiological surveys covering all regions and specific groups are recommended.

Indexed as

Antibodies, ViralFemaleHerpes SimplexHerpesvirus 1, HumanHerpesvirus 2, HumanHumansMaleNigeriaSeroepidemiologic StudiesSex FactorsAntibodies, ViralHerpes simplex virusinfectionmeta-analysisseroprevalencesystematic review

Identifiers

PMID31645218
PMCPMC6882437

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.