Evidence map›Paper›PMID 31645051›Full record

ArticlePediatric research2020

Relation of secondhand smoke exposure to vascular phenotypes in children and adolescents.

Michelle M Harbin, Aaron S Kelly, Donald R Dengel, Kyle D Rudser, Nicholas G Evanoff, Justin R Ryder

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michelle M HarbinLaboratory of Integrative Human Physiology, School of Kinesiology, University of Minnesota, Minneapolis, MN, 55455, USA. Harb0085@umn.edu.
Aaron S KellyDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
Donald R DengelLaboratory of Integrative Human Physiology, School of Kinesiology, University of Minnesota, Minneapolis, MN, 55455, USA.
Kyle D RudserCenter for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Nicholas G EvanoffLaboratory of Integrative Human Physiology, School of Kinesiology, University of Minnesota, Minneapolis, MN, 55455, USA.
Justin R RyderDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
University of Minnesota · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Validation of Circulating Endothelial Cells and Microparticles in YouthR01HL110957 · NHLBI · UNIVERSITY OF MINNESOTA · PI KELLY, AARON S · 2012 to 2016
$3.2M
NCATS NIH HHS UL1 TR002494NHLBI NIH HHS R01 HL110957
6 · The paper itself

Abstract

backgroundSubclinical cardiovascular risks of secondhand smoke (SHS) exposure among children and adolescents remains insufficiently described.

methodsThis was a cross-sectional study of 298 children and adolescents (48.0% male, body mass index: 27.0 ± 8.9 kg/m

resultsSHS was associated with lower abdominal aorta diameter distensibility (aDD) (13.4 ± 3.6% vs. 16.0 ± 5.2%, p = 0.009) and abdominal aorta cross-sectional distensibility (aCSD) (28.8 ± 8.3% vs. 35.1 ± 12.2%, p = 0.009), as well as higher abdominal aorta IEM (aIEM) (1241 ± 794 vs. 935 ± 388 mmHg, p = 0.001). After adjustment for covariates, aDD (p = 0.047), aCSD (p = 0.040), and aIEM (p = 0.017) remained significant; this significance persisted with the additional adjustment of percent body fat. Measures of brachial and carotid compliance and distensibility were not associated with SHS.

conclusionsSHS was associated with abdominal aorta stiffness; the majority of vascular measures within the brachial and carotid artery remained unaffected following adjustment for covariates, including hypertension and adiposity. SHS may predispose individuals to increased abdominal aorta stiffness, an artery previously reported to exhibit increased susceptibility to atherosclerosis.

Indexed as

Adolescent DevelopmentChild DevelopmentVascular StiffnessAdolescentAge FactorsAorta, AbdominalBrachial ArteryCarotid ArteriesChildCross-Sectional StudiesElastic ModulusFemaleHumansMaleRetrospective StudiesRisk AssessmentTobacco Smoke Pollution

Identifiers

PMID31645051
PMCPMC7082180
OpenAlexW2982194018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.