Evidence map›Paper›PMID 31644901›Full record

ArticleCell reports2019

Adult sox10

Marcos Sande-Melón, Inês J Marques, María Galardi-Castilla, Xavier Langa, María Pérez-López, Marius-Alexandru Botos, Héctor Sánchez-Iranzo, Gabriela Guzmán-Martínez, David Miguel Ferreira Francisco, Dinko Pavlinic and 3 more

Abstract read
In one paragraph

Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Mesenchymal-derived neural progenitors underlie localbioRxiv : the preprint server for biology · 2026
    Article
  5. Reactivation of an embryonic cardiac neural crest transcriptional profile during zebrafish heart regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Development of a hepatic cryoinjury model to study liver regeneration.bioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. The regenerative response of cardiac interstitial cells.Journal of molecular cell biology · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marcos Sande-MelónSpanish National Centre for Cardiovascular Research Carlos III (CNIC-ISCIII), 28029 Madrid, Spain; Institute of Anatomy, University of Bern, 3012 Bern, Switzerland.
Inês J MarquesInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland.
María Galardi-CastillaSpanish National Centre for Cardiovascular Research Carlos III (CNIC-ISCIII), 28029 Madrid, Spain.
Xavier LangaInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland.
María Pérez-LópezSpanish National Centre for Cardiovascular Research Carlos III (CNIC-ISCIII), 28029 Madrid, Spain.
Marius-Alexandru BotosInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland.
Héctor Sánchez-IranzoSpanish National Centre for Cardiovascular Research Carlos III (CNIC-ISCIII), 28029 Madrid, Spain.
Gabriela Guzmán-MartínezSpanish National Centre for Cardiovascular Research Carlos III (CNIC-ISCIII), 28029 Madrid, Spain; Departamento de Cardiología, Hospital Universitario La Paz. IdiPaz, 28046 Madrid, Spain.
David Miguel Ferreira FranciscoInterfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, 3012 Bern, Switzerland.
Dinko PavlinicGenomics Core Facility, European Molecular Biology Laboratory (EMBL) Heidelberg, 69117 Heidelberg, Germany.
Vladimir BenesGenomics Core Facility, European Molecular Biology Laboratory (EMBL) Heidelberg, 69117 Heidelberg, Germany.
Rémy BruggmannInterfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, 3012 Bern, Switzerland.
Nadia MercaderSpanish National Centre for Cardiovascular Research Carlos III (CNIC-ISCIII), 28029 Madrid, Spain; Institute of Anatomy, University of Bern, 3012 Bern, Switzerland. Electronic address: nadia.mercader@ana.unibe.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During heart regeneration in the zebrafish, fibrotic tissue is replaced by newly formed cardiomyocytes derived from preexisting ones. It is unclear whether the heart is composed of several cardiomyocyte populations bearing different capacity to replace lost myocardium. Here, using sox10 genetic fate mapping, we identify a subset of preexistent cardiomyocytes in the adult zebrafish heart with a distinct gene expression profile that expanded after cryoinjury. Genetic ablation of sox10

Indexed as

RegenerationAnimalsCell ProliferationCells, CulturedHeartMyocytes, CardiacSOXE Transcription FactorsZebrafishZebrafish Proteinssox10 protein, zebrafishSOXE Transcription FactorsZebrafish Proteinscardiomyocyte proliferationheart regenerationsox10zebrafish

Identifiers

PMID31644901
PMCPMC6856760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.