Evidence map›Paper›PMID 31643083›Full record

ArticleAmerican journal of physical anthropology2020

Ethical priority of the most actionable system of biomolecules: the metabolome.

Cecil M Lewis, Laura-Isobel McCall, Richard R Sharp, Paul G Spicer

Abstract read
In one paragraph

Article in American journal of physical anthropology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Chemical Cartography Approaches to Study Trypanosomatid Infection.Journal of visualized experiments : JoVE · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cecil M LewisUniversity of Oklahoma (OU) College of Arts and Sciences, Norman, OK.ORCID 0000-0002-2198-3427
Laura-Isobel McCallUniversity of Oklahoma (OU) College of Arts and Sciences, Norman, OK.
Richard R SharpMayo Clinic Biomedical Ethics Program, Rochester, MN.
Paul G SpicerUniversity of Oklahoma (OU) College of Arts and Sciences, Norman, OK.

Funding

Trust and Mistrust in American Indian and Alaska Native CommunitiesRM1HG009042 · NHGRI · UNIVERSITY OF OKLAHOMA · PI SPICER, PAUL G · 2016 to 2024
$8.5M
Microbial Ecologies of Indigenous CommunitiesR01GM089886 · NIGMS · UNIVERSITY OF OKLAHOMA · PI LAWSON, PAUL ALAN, LEWIS, CECIL M · 2011 to 2019
$2.4M
NHGRI NIH HHS RM1 HG009042NIGMS NIH HHS R01 GM089886
6 · The paper itself

Abstract

The metabolome is a system of small biomolecules (metabolites) and a direct result of human bioculture. Consequently, metabolomics is well poised to impact anthropological and biomedical research for the foreseeable future. Overall, we provide a perspective on the ethical, legal, and social implications (ELSI) of metabolomics, which we argue are often more alarming than those of genomics. Given the current mechanisms to fund research, ELSI beyond human DNA is stifled and in need of considerable attention.

Indexed as

GenomicsMetabolomeHumans

Identifiers

PMID31643083
PMCPMC7003909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.