Evidence map›Paper›PMID 31642700›Full record

ArticleEnvironmental health perspectives2019

Inter-host Transmission of Carbapenemase-Producing

Jiyun Li, Zhenwang Bi, Shizhen Ma, Baoli Chen, Chang Cai, Junjia He, Stefan Schwarz, Chengtao Sun, Yuqing Zhou, Jia Yin and 11 more

Erratum issuedAbstract read
In one paragraph

Article in Environmental health perspectives, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Human Cases of Carbapenemase-Producing Escherichia coli Linked to Spread Between Animals and the Environment in a Veterinary Facility-Massachusetts, USA, 2023.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  4. Antimicrobial resistantOne health (Amsterdam, Netherlands) · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Prevalence of ESBL-producingOne health (Amsterdam, Netherlands) · 2025
    Review
  11. Emergence and transmission of Carbapenem-resistantFrontiers in veterinary science · 2025
    Article
  12. Antimicrobial Resistance Profile ofActa medica Philippina · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Carbapenem-resistantJournal of water and health · 2024
    Article
  17. Article
  18. Article
  19. Clonal dissemination of highly virulentOne health (Amsterdam, Netherlands) · 2023
    Article
  20. Observational

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Jiyun LiBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhenwang BiShandong Academy of Clinical Medicine, Shandong Provincial Hospital, Jinan, Shandong, China.
Shizhen MaBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Baoli ChenShandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Center for Disease Control and Prevention, Jinan, Shandong, China.
Chang CaiChina Australia Joint Laboratory for Animal Health Big Data Analytics, College of Animal Science and Technology, Zhejiang Agricultural and Forestry University, Hangzhou, China.
Junjia HeBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Stefan SchwarzBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Chengtao SunBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yuqing ZhouBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Jia YinSchool of Health Care Management, Shandong University, Jinan, China.
Anette HulthDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Yongqiang WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhangqi ShenBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Shaolin WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Congming WuBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Lennart E NilssonDepartment of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Timothy R WalshBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Stefan BörjessonDepartment of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Jianzhong ShenBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Qiang SunSchool of Health Care Management, Shandong University, Jinan, China.
Yang WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.

Funding

Medical Research Council G1100135Medical Research Council MR/N028317/1Medical Research Council MR/P007295/1Medical Research Council MR/S013768/1
6 · The paper itself

Abstract

backgroundThe rapidly increasing dissemination of carbapenem-resistant Enterobacteriaceae (CRE) in both humans and animals poses a global threat to public health. However, the transmission of CRE between humans and animals has not yet been well studied.

objectivesWe investigated the prevalence, risk factors, and drivers of CRE transmission between humans and their backyard animals in rural China.

methodsWe conducted a comprehensive sampling strategy in 12 villages in Shandong, China. Using the household [residents and their backyard animals (farm and companion animals)] as a single surveillance unit, we assessed the prevalence of CRE at the household level and examined the factors associated with CRE carriage through a detailed questionnaire. Genetic relationships among human- and animal-derived CRE were assessed using whole-genome sequencing-based molecular methods.

resultsA total of 88 New Delhi

conclusionsTo our knowledge, we are the first to report evidence of direct transmission of NDM-EC between humans and animals. Given the rise of NDM-EC in community and hospital infections, combating NDM-EC transmission in backyard farm systems is needed. https://doi.org/10.1289/EHP5251.

Indexed as

Bacterial Proteinsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeEscherichia coliAnimalsAnimals, DomesticCattleChinaDogsDrug Resistance, Multiple, BacterialHumansSwineZoonosesBacterial Proteinsbeta-Lactamasescarbapenemase

Identifiers

PMID31642700
PMCPMC6910777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.