Evidence map›Paper›PMID 31642616›Full record

ArticleBirth defects research2019

Population-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects.

Erin B Stallings, Jennifer L Isenburg, Tyiesha D Short, Dominique Heinke, Russell S Kirby, Paul A Romitti, Mark A Canfield, Leslie A O'Leary, Rebecca F Liberman, Nina E Forestieri and 10 more

Abstract read
In one paragraph

Article in Birth defects research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Patient-Reported Long-Term Gastrointestinal Outcomes in Children with Omphalocele and Gastroschisis: A PedsQL GI Module Study.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2026
    Article
  4. Maternal Risk Factors for Omphalocele.Fetal diagnosis and therapy · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 1 country.

Erin B StallingsCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia.ORCID 0000-0002-0461-1410
Jennifer L IsenburgCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia.
Tyiesha D ShortCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia.
Dominique HeinkeMassachusetts Department of Public Health, Center for Birth Defects Research and Prevention, Boston, Massachusetts.ORCID 0000-0001-9217-3723
Russell S KirbyCollege of Public Health, University of South Florida, Tampa, Florida.ORCID 0000-0002-3489-401X
Paul A RomittiDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa.ORCID 0000-0001-5393-9984
Mark A CanfieldBirth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, Texas.
Leslie A O'LearyCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia.
Rebecca F LibermanMassachusetts Department of Public Health, Center for Birth Defects Research and Prevention, Boston, Massachusetts.ORCID 0000-0002-7593-4145
Nina E ForestieriDivision of Public Health, North Carolina Department of Health and Human Services, Raleigh, North Carolina.ORCID 0000-0001-7894-0279
Wendy N NembhardDepartment of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Arkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas.ORCID 0000-0002-8318-4049
Theresa SandidgeIllinois Department of Public Health, Springfield, Illinois.
Eirini NestoridiMassachusetts Department of Public Health, Center for Birth Defects Research and Prevention, Boston, Massachusetts.
Jason L SalemiDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-0077-6023
Amy E NanceUtah Birth Defect Network, Division of Family Health and Preparedness, Utah Department of Health, Salt Lake City, Utah.
Kirstan DuckettOhio Department of Health, Columbus, Ohio.
Glenda M RamirezArizona Birth Defects Monitoring Program, Arizona Department of Health Services, Phoenix, Arizona.
Xiaoyi ShanArkansas Reproductive Health Monitoring System, Arkansas Children's Research Institute, Little Rock, Arkansas.
Jing ShiSpecial Child Health and Early Intervention Services, New Jersey Department of Health, Trenton, New Jersey.
Philip J LupoDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0003-0978-5863
Centers for Disease Control and Prevention · USMassachusetts Department of Public Health · USBaylor College of Medicine · USArizona Department of Health Services · USArkansas Children's Hospital · USIllinois Department of Public Health · USNC Department of Health and Human Services · USNew Jersey Department of Health · USOak Ridge Associated Universities · USOhio Department of Health · USTexas Department of State Health Services · USUniversity of Arkansas for Medical Sciences · USUniversity of Iowa · USUniversity of South Florida · USUtah Department of Health · US

Funding

Iowa CBDRP: Component A BD-STEPS II CoreU01DD001223 · DD · UNIVERSITY OF IOWA · PI CONWAY, KRISTIN, ROMITTI, PAUL A · 2018 to 2022
$4.3M
Iowa CBDRP: Birth Defects Study To Evaluate Pregnancy exposureSU01DD001035 · DD · UNIVERSITY OF IOWA · PI ROMITTI, PAUL A · 2013 to 2017
$3.5M
Intramural CDC HHS CC999999NCBDD CDC HHS U01 DD001035NCBDD CDC HHS U01 DD001223
6 · The paper itself

Abstract

BACKGROUND/

objectivesIn this report, the National Birth Defects Prevention Network (NBDPN) examines and compares gastroschisis and omphalocele for a recent 5-year birth cohort using data from 30 population-based birth defect surveillance programs in the United States.

methodsAs a special call for data for the 2019 NBDPN Annual Report, state programs reported expanded data on gastroschisis and omphalocele for birth years 2012-2016. We estimated the overall prevalence (per 10,000 live births) and 95% confidence intervals (CI) for each defect as well as by maternal race/ethnicity, maternal age, infant sex, and case ascertainment methodology utilized by the program (active vs. passive). We also compared distribution of cases by maternal and infant factors and presence/absence of other birth defects.

resultsThe overall prevalence estimates (per 10,000 live births) were 4.3 (95% CI: 4.1-4.4) for gastroschisis and 2.1 (95% CI: 2.0-2.2) for omphalocele. Gastroschisis was more frequent among young mothers (<25 years) and omphalocele more common among older mothers (>40 years). Mothers of infants with gastroschisis were more likely to be underweight/normal weight prior to pregnancy and mothers of infants with omphalocele more likely to be overweight/obese. Omphalocele was twice as likely as gastroschisis to co-occur with other birth defects.

conclusionsThis report highlights important differences between gastroschisis and omphalocele. These differences indicate the importance of distinguishing between these defects in epidemiologic assessments. The report also provides additional data on co-occurrence of gastroschisis and omphalocele with other birth defects. This information can provide a basis for future research to better understand these defects.

Indexed as

Abdominal WallAbnormalities, MultipleAdultCongenital AbnormalitiesDigestive System AbnormalitiesFemaleGastroschisisHernia, UmbilicalHumansInfantInfant, NewbornLive BirthMaleMaternal AgeMiddle AgedMothersabdominal wall defectsbirth defectsgastroschisisNBDPNomphalocele

Identifiers

PMID31642616
PMCPMC6886260
OpenAlexW2982243977

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.