ArticlePaediatric and perinatal epidemiology2019
Relation of outbursts of anger and the acute risk of placental abruption: A case-crossover study.
Article in Paediatric and perinatal epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The Risk Factors for Placental Abruption in Preeclamptic Pregnancies: A Retrospective Case-Control Study.The journal of obstetrics and gynaecology research · 2026Article
- Causal effects of competing obstetrical interventions: mediators of placental abruption and perinatal mortality.American journal of epidemiology · 2025Article
- Epidemiology, Risk Factors, and Perinatal Outcomes of Placental Abruption-Detailed Annual Data and Clinical Perspectives from Polish Tertiary Center.International journal of environmental research and public health · 2022Article
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7 authors.
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Abstract
backgroundRoughly, a fourth of all placental abruption cases have an acute aetiologic underpinning, but the causes of acute abruption are poorly understood. Studies indicate that symptoms of stress, depression, and anxiety during pregnancy may be associated with a higher risk of abruption.
objectiveWe examined the rate of abruption in the 2 hours immediately following outbursts of anger.
methodsIn a multicentre case-crossover study, we interviewed 663 women diagnosed with placental abruption admitted to one of the seven Peruvian hospitals between January 2013 and August 2015. We asked women about outbursts of anger before symptom onset and compared this with their usual frequency of anger during the week before abruption.
resultsThe rate of abruption was 2.83-fold (95% confidence interval [CI] 1.85, 4.33) higher in the 2 hours following an outburst of anger compared with other times. The rate ratio (RR) was lower for women who completed technical school or university (RR 1.38, 95% CI 0.52, 3.69) compared to women with secondary school education or less (RR 3.73, 95% CI 2.32, 5.99, P-homogeneity = .07). There was no evidence that the association between anger episodes and abruption varied by hypertensive disorders of pregnancy (ie preeclampsia/ eclampsia) or antepartum depressive symptoms.
conclusionThere was a higher rate of abruption in the 2 hours following outbursts of anger compared with other times, providing potential clues to the aetiologic mechanisms of abruption of acute onset.
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