Evidence map›Paper›PMID 31642070›Full record

ArticleThe Journal of comparative neurology2020

Subregional differences in GABA

Patrick J Mueller, Bozena E Fyk-Kolodziej, Toni A Azar, Ida J Llewellyn-Smith

Open access · greenAbstract read
In one paragraph

Article in The Journal of comparative neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Patrick J MuellerDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan.ORCID 0000-0002-7720-1519
Bozena E Fyk-KolodziejDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan.
Toni A AzarDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan.
Ida J Llewellyn-SmithDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan.ORCID 0000-0003-4269-6846
Wayne State University · USFlinders University · AU

Funding

Inactivity and Enhanced Sympathoexcitation: Role of Neuroplasticity in the RVLMR01HL096787 · NHLBI · WAYNE STATE UNIVERSITY · PI MUELLER, PATRICK J · 2010 to 2018
$3.2M
NHLBI NIH HHS R01 HL096787
6 · The paper itself

Abstract

Neurons in the rostral ventrolateral medulla (RVLM) regulate blood pressure through direct projections to spinal sympathetic preganglionic neurons. Only some RVLM neurons are active under resting conditions due to significant, tonic inhibition by gamma-aminobutyric acid (GABA). Withdrawal of GABA

Indexed as

AnimalsMaleMedulla OblongataMotor ActivityNeuronsRatsRats, Sprague-DawleyReceptors, GABA-AReceptors, GABA-AbrainstemGABA receptorsinactivityneuroplasticityRRID:AB_2039862RRID:AB_2039864RRID:AB_2336904RRID:AB_310611sympathetic nerve activity

Identifiers

PMID31642070
PMCPMC7046220
OpenAlexW2981442138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.