Evidence map›Paper›PMID 31641905›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020

External validation of a prediction model for pain and functional outcome after elective lumbar spinal fusion.

Ayesha Quddusi, Hubert A J Eversdijk, Anita M Klukowska, Marlies P de Wispelaere, Julius M Kernbach, Marc L Schröder, Victor E Staartjes

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  4. Multicenter external validation of prediction models for clinical outcomes after spinal fusion for lumbar degenerative disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  5. Article
  6. Development and temporal validation of clinical prediction models for 1-year disability and pain after lumbar decompressive surgery. The Norwich Lumbar Surgery Predictor (development version).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  7. Predictors of poor outcome following lumbar spinal fusion surgery: a prospective observational study to derive two clinical prediction rules using British Spine Registry data.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Observational
  8. Article
  9. Development of a machine-learning based model for predicting multidimensional outcome after surgery for degenerative disorders of the spine.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Article
  10. Prediction of outcome after spinal surgery-using The Dialogue Support based on the Swedish national quality register.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ayesha QuddusiCenter for Neuroscience, Queens University, Kingston, ON, Canada.
Hubert A J EversdijkDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, Amsterdam, The Netherlands.
Anita M KlukowskaDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, Amsterdam, The Netherlands.
Marlies P de WispelaereDepartment of Clinical Informatics, Bergman Clinics, Amsterdam, The Netherlands.
Julius M KernbachDepartment of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Marc L SchröderDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, Amsterdam, The Netherlands.
Victor E StaartjesDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, Amsterdam, The Netherlands. victor.staartjes@gmail.com.ORCID 0000-0003-1039-2098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatient-reported outcome measures following elective lumbar fusion surgery demonstrate major heterogeneity. Individualized prediction tools can provide valuable insights for shared decision-making. We externally validated the spine surgical care and outcomes assessment programme/comparative effectiveness translational network (SCOAP-CERTAIN) model for prediction of 12-month minimum clinically important difference in Oswestry Disability Index (ODI) and in numeric rating scales for back (NRS-BP) and leg pain (NRS-LP) after elective lumbar fusion.

methodsData from a prospective registry were obtained. We calculated the area under the curve (AUC), calibration slope and intercept, and Hosmer-Lemeshow values to estimate discrimination and calibration of the models.

resultsWe included 100 patients, with average age of 50.4 ± 11.4 years. For 12-month ODI, AUC was 0.71 while the calibration intercept and slope were 1.08 and 0.95, respectively. For NRS-BP, AUC was 0.72, with a calibration intercept of 1.02, and slope of 0.74. For NRS-LP, AUC was 0.83, with a calibration intercept of 1.08, and slope of 0.95. Sensitivity ranged from 0.64 to 1.00, while specificity ranged from 0.38 to 0.65. A lack of fit was found for all three models based on Hosmer-Lemeshow testing.

conclusionsThe SCOAP-CERTAIN tool can accurately predict which patients will achieve favourable outcomes. However, the predicted probabilities-which are the most valuable in clinical practice-reported by the tool do not correspond well to the true probability of a favourable outcome. We suggest that any prediction tool should first be externally validated before it is applied in routine clinical practice. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

Spinal FusionAdultAgedFemaleHumansLumbar VertebraeLumbosacral RegionMaleMiddle AgedPainTreatment OutcomeExternal validationLumbar fusionOutcome predictionPatient-reported outcomePredictive analytics

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.