Evidence map›Paper›PMID 31641900›Full record

ArticleEuropean child & adolescent psychiatry2020

Sex-linked neurofunctional basis of psychological resilience in late adolescence: a resting-state functional magnetic resonance imaging study.

Song Wang, Cheng Yang, Yajun Zhao, Han Lai, Lei Zhang, Qiyong Gong

Abstract read
PubMed Publisher
In one paragraph

Article in European child & adolescent psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Song WangHuaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, People's Republic of China.
Cheng YangHuaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, People's Republic of China.
Yajun ZhaoSchool of Sociology and Psychology, Southwest Minzu University, Chengdu, 610041, People's Republic of China.
Han LaiHuaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, People's Republic of China.
Lei ZhangPsychoradiology Research Unit of Chinese Academy of Medical Sciences (2018RU011), West China Hospital of Sichuan University, Chengdu, 610041, People's Republic of China.
Qiyong GongHuaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, People's Republic of China. qiyonggong@hmrrc.org.cn.
West China Hospital of Sichuan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNSichuan University · CNSouthwest Minzu University · CNWest China Medical Center of Sichuan University · CN

Funding

Changjiang Scholar Professorship Award of China T2014190the American CMB Distinguished Professorship Award F510000/G16916411the China Postdoctoral Science Foundation Grant No. 2019M653421the National Natural Science Foundation Grant No. 31800963the National Natural Science Foundation of China 81621003the National Natural Science Foundation of China 81820108018the Program for Changjiang Scholars and Innovative Research Team in University Grant No. IRT16R52
6 · The paper itself

Abstract

Psychological resilience refers to the ability to adapt effectively in the face of adversity, which is closely related to an individual's psychological and physical health and well-being. Although previous behavioural studies have shown sex differences in psychological resilience, little is known about the neural basis of sex differences in psychological resilience. Here, we measured amplitude of low-frequency fluctuations (ALFF) via resting-state functional magnetic resonance imaging to investigate the sex-linked neurofunctional basis of psychological resilience in 231 healthy adolescents. At the behavioural level, we replicated previous findings indicating that males are more resilient than females. At the neural level, we found sex differences in the relationship between psychological resilience and ALFF in the right orbitofrontal cortex (OFC). Specifically, males showed a positive correlation between psychological resilience and ALFF in the right OFC, while females showed a negative correlation in this region. The sex-specific association between psychological resilience and spontaneous brain activity might be dependent on differences in hormonal systems and brain development between male and female adolescents. Taken together, the results of our study might provide the first evidence of sex-specific neurofunctional substrates of psychological resilience in adolescents, emphasizing the vital role of sex effects in future psychological resilience-related studies.

Indexed as

AdolescentAdultBrainFemaleHumansMagnetic Resonance ImagingMaleResilience, PsychologicalSex CharacteristicsAnxietyOrbitofrontal cortexPsychological resilienceResting-state fMRISex differencesStress

Identifiers

PMID31641900
OpenAlexW2981991068

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.