Evidence map›Paper›PMID 31641855›Full record

SynthesisLangenbeck's archives of surgery2019

Central pancreatectomy: a comprehensive, up-to-date meta-analysis.

Mihnea P Dragomir, Alexandru A Sabo, George E D Petrescu, Yongfeng Li, Traian Dumitrascu

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Langenbeck's archives of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 46 citations in OpenAlex.

  1. Central pancreatectomy: a Latin American experience of parenchyma-sparing surgery for benign and low-grade pancreatic neoplasms.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
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  2. Review
  3. ArtiSential-assisted laparoscopic central pancreatectomy.Journal of minimally invasive surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Mihnea P DragomirCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Alexandru A SaboDepartment of Pediatrics, "Marie S. Curie" Emergency Clinical Hospital for Children, Bucharest, Romania.
George E D PetrescuCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Yongfeng LiDepartment of Breast Surgery, Zhejiang Cancer Hospital, Hangzhou, People's Republic of China.
Traian DumitrascuCarol Davila University of Medicine and Pharmacy, Bucharest, Romania. traian.dumitrascu@umfcd.ro.
Carol Davila University of Medicine and Pharmacy · ROSpitalului Clinic de Urgență pentru Copii Maria Sklodowska Curie · ROZhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral pancreatectomy (CP) is the alternative to distal pancreatectomy (DP) for specific pathologies of the mid-pancreas. However, the benefits of CP over DP remain controversial. This study aims to compare the two procedures by conducting a meta-analysis of all published papers.

methodsA systematic search of original studies comparing CP vs. DP was performed using PubMed, Scopus, and Cochrane Library databases up to June 2018. The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) checklist was followed.

resultsTwenty-one studies were included (596 patients with CP and 1070 patients with DP). Compared to DP, CP was associated with significantly higher rates of overall and severe morbidity (p < 0.0001), overall and clinically relevant pancreatic fistula (p < 0.0001), postoperative hemorrhage (p = 0.02), but with significantly lower incidences of new-onset (p < 0.0001) and worsening diabetes mellitus (p = 0.004). Furthermore, significantly longer length of hospital stay (p < 0.0001) was observed for CP patients.

conclusionsCP is superior to DP regarding the preservation of pancreatic functions, but at the expense of significantly higher complication rates and longer hospital stay. Proper selection of patients is of utmost importance to maximize the benefits and mitigate the risks of CP.

Indexed as

Disease-Free SurvivalFemaleHumansLaparoscopyLength of StayMaleNeoplasm InvasivenessNeoplasm StagingOpen Abdomen TechniquesOperative TimePancreasPancreatectomyPancreatic NeoplasmsPatient SelectionPostoperative ComplicationsPrognosisCentral pancreatectomyDiabetes mellitusDistal pancreatectomyExocrine pancreatic insufficiencyMorbidity

Identifiers

PMID31641855
OpenAlexW2981495451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.