ArticleThe journal of nutrition, health & aging2019
Midlife Body Mass Index Trajectory and Risk of Frailty 8 Years Later in Taiwan.
Article in The journal of nutrition, health & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Low Body Mass Index Increases Frailty Risk in Old-Old Adults: Findings From a 3-Year Longitudinal Study.Geriatrics & gerontology international · 2026Article
- Long-term variability in physiological measures and risk of frailty: evidence from two cohort studies.The journal of nutrition, health & aging · 2026Article
- Body mass index trajectories in older adulthood and all-cause mortality: a cohort study in China.BMC public health · 2025Article
- Factors Associated with Frailty Transitions Using the Kihon Checklist: A 6-Year Longitudinal Study Among Japanese Residents.Clinical interventions in aging · 2025Article
- Association of BMI trajectories and healthy aging among Chinese older adults: a national cohort study.Frontiers in public health · 2025Article
- Mid-life plasma proteins associated with late-life prefrailty and frailty: a proteomic analysis.GeroScience · 2024Article
- The association between frailty and body composition among the elderly: Birjand Longitudinal Aging Study (BLAS).Journal of diabetes and metabolic disorders · 2024Article
- Determining factors that maintain physical function or increase frailty using the Kihon checklist among community-dwelling older adults: a six-year longitudinal study in Agano, Japan.BMC geriatrics · 2023Article
- Long-term variability in physiological measures in relation to mortality and epigenetic aging: prospective studies in the USA and China.BMC medicine · 2023Article
- Body mass index and physical frailty among older Mexican Americans: Findings from an 18-year follow up.PloS one · 2022Article
- Article
- Five-year longitudinal study of frailty prevalence and course assessed using the Kihon Checklist among community-dwelling older adults in Japan.Scientific reports · 2021Article
- Fruit and vegetable intake and risk of frailty in women 60 years old or older.The American journal of clinical nutrition · 2020Article
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4 authors.
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Abstract
objectivesFew studies have focused on weight change and frailty, especially in Asia. This research aimed to evaluate midlife body mass index (BMI) trajectory and assess its relationship with frailty 8 years later in Taiwan.
designA prospective cohort study. SETTING AND
participantsData were retrieved from the Taiwan Longitudinal Study on Aging conducted from 1999 to 2007. The analysis was restricted to respondents aged between 50 to 69 years old, who were not frail in 1999 and were alive in 2007 (n=1609). MEASUREMENTS: Frailty was defined using the Fried criteria. The group-based model of trajectory was used to estimate BMI trajectories among elderly participants. Logistic regression analysis was used to examine the association between BMI change and frailty.
resultsFour trajectory classes were identified and each remained stable during the 8-year follow-up. There were 316 participants (20.3%) in the low-normal weight group (baseline BMI=20.38 kg/m2), 737 participants (44.7%) in the high-normal weight group (baseline BMI=23.22 kg/m2), 449 participants (28.4%) in the overweight group (baseline BMI=26.24 kg/m2), and 107 participants (6.6%) in the obesity group (baseline BMI=30.65 kg/m2). After adjustment for confounding factors, the low-normal weight group and obesity group were associated with increased frailty compared with the high-normal weight group.
conclusionOur results showed that the BMI trajectories of midlife individuals tended to be constant and those in both the low-normal weight group and obesity group had an increased risk of developing frailty in later life. Therefore, an optimal weight-targeting strategy should be considered for Asian elderly individuals.
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