Evidence map›Paper›PMID 31641694›Full record

ArticleWellcome open research2019

Adverse events with ayurvedic medicines- possible adulteration and some inherent toxicities.

Buddhi Paudyal, Astha Thapa, Keshav Raj Sigdel, Sudeep Adhikari, Buddha Basnyat

Open access · goldAbstract readCase Reports
In one paragraph

Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Ayurvedic Ingredients in Dermatology: A Call for Research.Journal of cosmetic dermatology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Anthelmintic evaluation of three ayurvedic formulations: a transmission electron microscopy study inJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  8. Article
  9. Astounding Health Benefits of Jamun (Molecules (Basel, Switzerland) · 2022
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Buddhi PaudyalDepartment of Internal Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal.ORCID https://orcid.org/0000-0002-5119-4082
Astha ThapaDepartment of Internal Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal.ORCID https://orcid.org/0000-0002-4374-0338
Keshav Raj SigdelDepartment of Internal Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal.
Sudeep AdhikariDepartment of Internal Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal.ORCID https://orcid.org/0000-0003-2659-3425
Buddha BasnyatDepartment of Internal Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal.ORCID https://orcid.org/0000-0002-1125-2743
Patan Academy of Health Sciences · NP

Funding

Wellcome Trust
6 · The paper itself

Abstract

Ayurvedic medicine, a traditional system of medicine practiced in the Indian subcontinent is considered to be devoid of adverse events. We report three cases which highlight the possibility of adverse events related with the use of ayurvedic products. A 35 year old woman with hepatitis took ayurvedic powder medicine and swarnabhasma (gold salt) and had her liver injury worsened, possibly due to alkaloids, and developed nephrotic syndrome, possibly due to gold salt. A 57 year old hypertensive man was taking ayurvedic medicine containing reserpine which had long been withdrawn from the allopathic system of medicine due to wide range of side effects. A 47 year old woman with rheumatoid arthritis was taking an unknown tablet containing steroid as an adulterant for 2 years and developed side effects typical of steroid excess. We would like to highlight the fact that ayurvedic medicines do have propensity to cause adverse events due to adulteration or inherent constituents like alkaloids, and hence may not always be completely safe.

Indexed as

adulterationalkaloidsAyurvedic medicineheavy metals

Identifiers

PMID31641694
PMCPMC6790910
OpenAlexW2964470905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.