Evidence map›Paper›PMID 31641663›Full record

ArticleAutopsy & case reports

Warthin-like mucoepidermoid carcinoma of the parotid gland: a diagnostic and therapeutic dilemma.

Vigneshwaran Balasubiramaniyan, Mahesh Sultania, Mukund Sable, Dillip Muduly, Madhabananda Kar

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Autopsy & case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Parotid Gland Tumors: Molecular Diagnostic Approaches.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vigneshwaran BalasubiramaniyanAll India Institute of Medical Sciences, Department of Surgical Oncology. Bhubaneswar, Sijua, Orissa, India.ORCID https://orcid.org/0000-0002-9420-704X
Mahesh SultaniaAll India Institute of Medical Sciences, Department of Surgical Oncology. Bhubaneswar, Sijua, Orissa, India.ORCID https://orcid.org/0000-0003-1008-8694
Mukund SableAll India Institute of Medical Sciences, Department of Pathology. Bhubaneswar, Sijua, Orissa, India.ORCID https://orcid.org/0000-0002-5364-1464
Dillip MudulyAll India Institute of Medical Sciences, Department of Surgical Oncology. Bhubaneswar, Sijua, Orissa, India.ORCID https://orcid.org/0000-0001-6427-5714
Madhabananda KarAll India Institute of Medical Sciences, Department of Surgical Oncology. Bhubaneswar, Sijua, Orissa, India.
All India Institute of Medical Sciences Bhubaneswar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor. Although the parotid gland is the most common site of involvement, other major salivary glands and the minor salivary glands-most commonly of the palate-also can be involved. The management of mucoepidermoid carcinoma depends on the grade of the tumor and the adequacy of resection. We present the case of a 56-year-old female presenting a painless progressive cheek mass over 2 months. Imaging and fine-needle aspiration cytology provided the diagnosis of Mucoepidermoid carcinoma. A superficial parotidectomy was done, and the histopathology revealed a predominantly cystic tumor with a bilayered epithelium of oncocytic and basal cells. Moderate nuclear pleomorphism with infiltration of atypical squamous cells in few glandular cysts was seen. Special staining revealed the presence of intracellular mucin. A diagnosis of Warthin-like variant of MEC was made, based on these findings. After the surgical procedures, the patient is disease-free at 8 months of follow-up. The Warthin-like variant is a rare variant of MEC with fewer than 10 cases described in the English literature. Various differential diagnoses include the malignant transformation of Wartin tumor (WT), squamous metaplasia of WT, and metastasis from a distant primary. We emphasize the role of routine microscopy in identifying rare variants of common malignancies. Even though translocation studies are helpful in diagnosis, the typical histopathological findings should confirm it.

Indexed as

Carcinoma, MucoepidermoidParotid NeoplasmSalivary Gland Neoplasms

Identifiers

PMID31641663
PMCPMC6771442
OpenAlexW2979075321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.