Evidence map›Paper›PMID 31641659›Full record

ArticleAutopsy & case reports

Intraoral EBV-positive sporadic Burkitt lymphoma in an elderly patient with bilateral presentation.

Ricardo Martínez Pedraza, Lady Paola Aristizabal Arboleda, Celeste Sánchez-Romero, Jesús Alfonso Aguirre Quiñones, Carlos de Jesús Mata Tovar, Javier Rendón Henao, Oslei Paes de Almeida

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Autopsy & case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Ricardo Martínez PedrazaUniversidad Autónoma de Nuevo León, School of Dentistry, Department of Advance General Dental Master. Monterrey, Nuevo León, México.ORCID https://orcid.org/0000-0003-0046-0026
Lady Paola Aristizabal ArboledaUniversity of Campinas, Piracicaba Dental School, Department of Oral Diagnosis, Oral Pathology Section. Piracicaba, SP, Brazil.ORCID https://orcid.org/0000-0002-6090-1893
Celeste Sánchez-RomeroUniversity of Campinas, Piracicaba Dental School, Department of Oral Diagnosis, Oral Pathology Section. Piracicaba, SP, Brazil.ORCID https://orcid.org/0000-0001-5365-2692
Jesús Alfonso Aguirre QuiñonesUniversidad Autónoma de Coahuila, School of Dentistry, Dental Sciences Master. Torreón, Coahuila, México.ORCID https://orcid.org/0000-0002-3359-2749
Carlos de Jesús Mata TovarUniversidad Veracruzana, School of Dentistry, Forensic Medicine Master. Veracruz, Veracruz, México.ORCID https://orcid.org/0000-0001-9262-7334
Javier Rendón HenaoUniversidad de Antioquia, Medical School. Medellín, Colombia.
Oslei Paes de AlmeidaUniversity of Campinas, Piracicaba Dental School, Department of Oral Diagnosis, Oral Pathology Section. Piracicaba, SP, Brazil.ORCID https://orcid.org/0000-0003-2002-8003
Methodist University of Piracicaba · BRUniversidad Autónoma de Coahuila · MXUniversidad Autónoma de Nuevo León · MXUniversidad de Antioquia · COUniversidad Veracruzana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sporadic Burkitt lymphoma (SBL) is a variant of Burkitt lymphoma that occurs worldwide, affecting mainly children and young adults. Association with Epstein-Barr virus (EBV) can be identified in approximately 20-30% of cases. Herein we described a case of a 63-year-old male presenting intraoral bilateral mandibular swelling, subjacent to fixed dental prosthesis, with one month of duration. Incisional biopsies were performed, and after two days, the patient was hospitalized due to malaise and breathing difficulty, and died after a week when an abdominal tumor was detected. The mandibular biopsies revealed a diffuse proliferation of medium-sized monomorphic atypical lymphoid cells exhibiting numerous mitoses and areas of "starry-sky" pattern. The tumor showed immunohistochemical positivity for CD20, CD10, Bcl-6, and Ki-67 (≈ 100%); it was negative for CD3, Bcl-2, Vs38c, and MUM-1. Positivity for EBV was found by in situ hybridization. The final diagnosis was intraoral SBL positive for EBV. Clinical, morphological and molecular criteria are necessary for the correct diagnosis of aggressive B-cell neoplasms positive for EBV in elderly patients.

Indexed as

Burkitt lymphomaEpstein-Barr virusMouth neoplasmsNon-Hodgkin Lymphoma

Identifiers

PMID31641659
PMCPMC6771441
OpenAlexW2974142056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.