Evidence map›Paper›PMID 31641590›Full record

ArticleMolecular genetics and metabolism reports2019

Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy.

Remi Stevelink, Faith Pangilinan, Floor E Jansen, Kees P J Braun, International League Against Epilepsy Consortium on Complex Epilepsies, Anne M Molloy, Lawrence C Brody, Bobby P C Koeleman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Global impact of micronutrients in modern human evolution.American journal of human genetics · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Remi StevelinkDepartment of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Faith PangilinanNational Human Genome Research Institute, National Institutes of Health, Bethesda, USA.
Floor E JansenDepartment of Child Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
Kees P J BraunDepartment of Child Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
International League Against Epilepsy Consortium on Complex Epilepsies
Anne M MolloySchool of Medicine, Trinity College Dublin, Dublin, Ireland.
Lawrence C BrodyNational Human Genome Research Institute, National Institutes of Health, Bethesda, USA.
Bobby P C KoelemanDepartment of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
University Medical Center Utrecht · NLNational Institutes of Health · USTrinity College Dublin · IEUtrecht University · NL

Funding

Department of Health 09/144/09Medical Research Council G0800637
6 · The paper itself

Abstract

Altered vitamin B6 metabolism due to pathogenic variants in the gene

Indexed as

GeneticsGGEGWASPharmacogeneticsPyridoxineSNP

Identifiers

PMID31641590
PMCPMC6796782
OpenAlexW2979379861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.