ReviewPneumonia (Nathan Qld.)2015
The respiratory microbiota during health and disease: a paediatric perspective.
Review in Pneumonia (Nathan Qld.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Corticosteroids on the Respiratory Microbiome: A Systematic Review.Frontiers in medicine · 2021Pooled it
- Landscape of the upper and lower airway microbiota in children with community-acquired pneumonia.Virulence · 2026Article
- Crosstalk between the microbiome and the mucosal immunoglobulin A system in the lung, in health and disease.Frontiers in cellular and infection microbiology · 2026Review
- Respiratory Microbiota and Health Risks in Children with Cerebral Palsy: A Narrative Review.Children (Basel, Switzerland) · 2025Review
- The neonate respiratory microbiome.Acta physiologica (Oxford, England) · 2025Review
- The possible role of particulate matter on the respiratory microbiome: evidence from in vivo to clinical studies.Archives of toxicology · 2023Review
- Nasal Bacteriomes of Patients with Asthma and Allergic Rhinitis Show Unique Composition, Structure, Function and Interactions.Microorganisms · 2023Article
- Environmental factors related to differences in the microbiota in the upper respiratory tract in young children: Focusing on the impact of early nursery attendance.Frontiers in pediatrics · 2023Article
- Respiratory dysbiosis in cats with spontaneous allergic asthma.Frontiers in veterinary science · 2022Article
- Frequent exacerbators of chronic obstructive pulmonary disease have distinguishable sputum microbiome signatures during clinical stability.Frontiers in microbiology · 2022Article
- Comparison of microbiota in the upper versus lower respiratory tract in children during health and respiratory disease: protocol for a systematic review.Systematic reviews · 2021Article
- Dysbiosis in Pediatrics Is Associated with Respiratory Infections: Is There a Place for Bacterial-Derived Products?Microorganisms · 2021Review
- The porcine respiratory microbiome: recent insights and future challenges.Animal microbiome · 2021Review
- [Role of gut microbiota in children with allergic rhinitis with high serum total IgE level].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020Article
- Metagenomics Reveals That Intravenous Injection of Beta-Hydroxybutyric Acid (BHBA) Disturbs the Nasopharynx Microflora and Increases the Risk of Respiratory Diseases.Frontiers in microbiology · 2020Article
- Anterior Nares Diversity and Pathobionts Represent Sinus Microbiome in Chronic Rhinosinusitis.mSphere · 2019Article
- Bacterial-Host Interactions: Physiology and Pathophysiology of Respiratory Infection.Physiological reviews · 2018Review
- Port d'Entrée for Respiratory Infections - Does the Influenza A Virus Pave the Way for Bacteria?Frontiers in microbiology · 2017Review
- Development of Upper Respiratory Tract Microbiota in Infancy is Affected by Mode of Delivery.EBioMedicine · 2016Article
- 16S rRNA deep sequencing for the characterization of healthy human pharyngeal microbiome.HippokratiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies investigating the relationship between the microbiota and disease are demonstrating novel concepts that could significantly alter the way we treat disease and promote health in the future. It is suggested that the microbiota acquired during childhood may shape the microbial community and affect immunological responses for later life, and could therefore be important in the susceptibility towards disease. Several diseases, including asthma, pneumonia, and otitis media, are associated with changes in composition and diversity of the respiratory microbiota. This review summarises current literature, focusing on the composition and development of the respiratory microbiota in children and its relationship with respiratory diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.