ArticleHippokratia
Surgical treatment of metastasis to the thyroid gland: a single center experience and literature review.
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Who cites it
12 citing papers in PubMed.
- Thyroid Metastasis as the Initial Presentation of Occult Breast Carcinoma: A Case Report.Cureus · 2026Article
- Diagnosis and treatment of breast cancer metastasis to thyroid: a case report and literature review.Frontiers in surgery · 2026Article
- Metastasis of clear cell renal cell carcinoma to hyalinizing trabecular tumor of the thyroid: A case report.Oncology letters · 2025Article
- Metastasis to Thyroid from Recurrent Head and Neck Squamous Cell Carcinoma: A Case Series and Review of Literature.Indian journal of surgical oncology · 2025Article
- Thyroid metastasis from hepatocellular carcinoma: a rare case report and literature review.Frontiers in oncology · 2025Article
- A Rare Case of Thyroid Metastasis From Colorectal Cancer: Diagnostic and Therapeutic Challenges.Cureus · 2023Article
- The clinical and histopathological characteristics of thyroid gland diseases in adolescents requiring surgical treatment: a ten-year follow-up study.Nagoya journal of medical science · 2023Article
- Neuroendocrine neoplasm with metastasis to the thyroid: a case report and literature review.Frontiers in oncology · 2023Article
- Metastases to the Thyroid Gland: What Can We Do?Cancers · 2022Review
- Clinicopathological and Molecular Features of Secondary Cancer (Metastasis) to the Thyroid and Advances in Management.International journal of molecular sciences · 2022Review
- Metastases to the thyroid gland: review of incidence, clinical presentation, diagnostic problems and surgery, our experience.Journal of endocrinological investigation · 2020Article
- PRMT5 Promotes Aerobic Glycolysis and Invasion of Breast Cancer Cells by Regulating the LXRα/NF-κBp65 Pathway.OncoTargets and therapy · 2020Article
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4 authors.
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Abstract
backgroundMetastasis to the thyroid gland or nonthyroid malignancy (NTM) is rarely an indication for thyroidectomy and constitute 1-3 % of all thyroid carcinomas. NTM has a poor prognosis, due to the advanced stage of the primary tumor. This study aimed to present the incidence, clinical characteristics, and treatment outcome of NTM in a single, high volume center. CASE SERIES: We retrospectively analyzed all patients who had undergone thyroidectomy at the Center for Endocrine Surgery in Belgrade, during the period from 1995 to 2015. Out of 13,385 patients who were submitted to thyroidectomy, 3,344 (24.2 %) patients had thyroid malignancy. The diagnosis of NTM, based on the histopathological findings, was found in ten patients (0.075 % of all patients who had thyroid surgery, i.e., in 0.3 % of patients with thyroid cancer), with a mean age of 59.5 years. The most frequent primary tumor location in NTM was kidney in four patients, esophagus in two patients, and pharynx, breast and lungs (one case each). Total thyroidectomy was performed in four patients and lobectomy in two patients. Mean survival time following thyroid surgery was 43.2 months.
conclusionNTM are uncommon, and their prognosis is generally poor and depends on the characteristics of the primary tumor. Nevertheless, in selected cases, surgical treatment of NTM should be considered. HIPPOKRATIA 2018, 22(3): 137-140.
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