Evidence map›Paper›PMID 31641325›Full record

Trial reportEthnicity & disease2019

Stress Reduction in the Prevention of Left Ventricular Hypertrophy: A Randomized Controlled Trial of Transcendental Meditation and Health Education in Hypertensive African Americans.

Robert H Schneider, Hector F Myers, Komal Marwaha, Maxwell A Rainforth, John W Salerno, Sanford I Nidich, Carolyn Gaylord-King, Charles N Alexander, Keith C Norris

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Ethnicity & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05373732 (Stress Reduction in the Prevention of Left Ventricular Hypertrophy), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05373732 nacompletednot on this map

Stress Reduction in the Prevention of Left Ventricular Hypertrophy: A Randomized Controlled Trial of Transcendental Meditation and Health Education in Hypertensive African Americans

TypeinterventionalSponsorMaharishi International UniversityRan1996 to 1998Enrolled171ConditionsLeft Ventricular Hypertrophy, High Blood PressureArmsmeditation, Health education control
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Impact of transcendental meditation on left ventricular mass in african american adolescents.Evidence-based complementary and alternative medicine : eCAM · 2012
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robert H SchneiderInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
Hector F MyersVanderbilt University, Vanderbilt Place, Nashville, Tennessee, USA.
Komal MarwahaInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
Maxwell A RainforthInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
John W SalernoInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
Sanford I NidichInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
Carolyn Gaylord-KingInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
Charles N AlexanderInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, IA, USA.
Keith C NorrisDavid Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: African Americans have disproportionately high rates of cardiovascular disease (CVD). Left ventricular hypertrophy (LVH) is an independent risk factor for CVD and may contribute to this disparity. Psychological stress contributes to LVH in African Americans and other populations. Objective: This study evaluated the effects of stress reduction with the Transcendental Meditation (TM) technique on preventing LVH in African American adults with hypertension. Setting: Martin Luther King Hospital - Charles R. Drew University of Medicine and Science, Los Angeles, CA. Method: In this trial, 85 African American adults (average 52.8 years) were randomly assigned to either TM program or health education (HE) control group and completed posttesting. Participants were tested at baseline and after six months for left ventricular mass index (LVMI) by M-mode echocardiography, blood pressure, psychosocial stress and behavioral factors. Change in outcomes was analyzed between groups by ANCOVA and within groups by paired t-test. Results: The TM group had significantly lower LVMI compared with the HE group (-7.55gm/m Conclusions: These findings indicate that stress reduction with TM was effective in preventing LVMI progression and thus may prevent LVH and associated CVD in high-risk African American patients.

Indexed as

MeditationPatient Education as TopicAdultBlack or African AmericanBlood PressureEchocardiographyFemaleHumansHypertensionHypertrophy, Left VentricularLife StyleMaleMiddle AgedRisk FactorsSingle-Blind MethodStress, PsychologicalCardiovascular DiseaseHealth DisparityLeft Ventricular HypertrophyLeft Ventricular Mass IndexStress ReductionTranscendental Meditation

Identifiers

PMID31641325
PMCPMC6802172

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.