ArticleVeterinary world2019
Evaluation of hepatobiliary ultrasound scores in healthy dogs and dogs with liver diseases.
Article in Veterinary world, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Ultrasonographic Gallbladder Findings and Bile Culture Results in Dogs with Extrahepatic Biliary Disorders: A Retrospective Exploratory Case Series.Life (Basel, Switzerland) · 2026Article
- B-Mode Ultrasonographic Evaluation and Reference Dimensions of the Liver and Spleen in Healthy Lactating Saanen Goats.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026Article
- Serum Liposoluble Vitamins (A, D, E) in Dogs with Chronic Biliary Tract Diseases Versus Healthy Dogs.Veterinary sciences · 2025Article
- Clinical utility of two-dimensional shear wave elastography in two dogs with presumptive toxic hepatopathy.Journal of veterinary science · 2025Article
- ORNIPURALFrontiers in veterinary science · 2025Article
- Ultrasound elastography in dogs: Physical principles and application in intestinal evaluation.Veterinary world · 2024Review
- Predictive Factors of Canine Malignant Hepatic Diseases with Multifocal Hepatic Lesions Using Clinicopathology, Ultrasonography, and Hepatobiliary Ultrasound Scores.Animals : an open access journal from MDPI · 2024Article
- Critical Advances for Democratizing Ultrasound Diagnostics in Human and Veterinary Medicine.Annual review of biomedical engineering · 2024Review
- Use of New Ultrasonography Methods for Detecting Neoplasms in Dogs and Cats: A Review.Animals : an open access journal from MDPI · 2024Review
- Serum Bile Acids Concentrations and Liver Enzyme Activities after Low-Dose Trilostane in Dogs with Hyperadrenocorticism.Animals : an open access journal from MDPI · 2023Article
- Predictive Factors for Two-Year Survival in Dogs with Hepatobiliary Diseases: Importance of Clinical and Laboratory Monitoring.Animals : an open access journal from MDPI · 2023Article
- Changes in Serum Lipid Profiles among Canine Patients Suffering from Chronic Hepatitis.Veterinary sciences · 2021Article
- A descriptive study of the histopathologic and biochemical liver test abnormalities in dogs with liver disease in Thailand.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimUltrasonography is the first-line method for examining the canine liver. Hepatic ultrasound scoring systems are widely described in human medicine, yet there is no information on the use of semi-quantitative ultrasound scoring systems in canine liver diseases. This study aimed to evaluate the hepatobiliary ultrasound scores between physically healthy dogs and dogs with primary liver diseases confirmed by clinical, biochemical, and histological parameters. We also evaluated the putative correlations between ultrasound scores and ALT or ALP levels. Moreover, the severity of ultrasound scoring and fold changes in liver enzymes was also evaluated. MATERIALS AND
methodsA cross-sectional study design was conducted to compare the results of the six different parameters (liver surface, echogenicity of parenchyma, nodularity of parenchyma, gallbladder wall thickness, amount of gall sludge, and visibility of bile duct) of ultrasound scores between dogs with and without liver disease.
resultsOur results showed that 17.4%, 88.2%, and 100% of dogs with liver diseases were identified according to the ultrasound severity classified as mild (total score 0-2), moderate (total score 3-5), and severe (total score 6-12). Approximately 30% of patients with chronic hepatitis, the most common canine liver disease, presented with normal or mild ultrasound score category, whereas most of the patients with vacuolar hepatopathy and steroid-induced hepatopathy due to secondary reactive changes had moderate-to-severe ultrasound score category. There were 75% of patients with tumor and 80% of patients with hepatic fibrosis that were identified with severe ultrasound score category. Dogs with moderate-to-severe ultrasound scores had significant liver enzyme elevation (both alanine aminotransferase [ALT] and alkaline phosphatase [ALP]) compared to those of dogs with mild ultrasound scores. Ultrasound score was moderately associated with ALT and highly associated with ALP levels (p=0.553 and p=0.730, respectively).
conclusionOur semi-quantitative, simplified ultrasonographic scoring system may have potential to be used as a screening tool to detect some groups of liver diseases.
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