ArticleScientific reports2019
Transcranial random noise stimulation (tRNS): a wide range of frequencies is needed for increasing cortical excitability.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- The effects of transcranial random noise stimulation on excitation/inhibition balance in ADHD.NeuroImage. Clinical · 2026Trial
- Online HD-tRNS Over the Right Temporoparietal Junction Modulates Social Inference But Not Motor Coordination.eNeuro · 2025Trial
- Improving Peripheral Reading With Noninvasive Transcranial Electrical Stimulation of Early Visual Areas.Translational vision science & technology · 2025Trial
- Effects of a Single Session 400 Hz Transcranial Pulsed Current Stimulation on Corticospinal and Corticocortical Excitability and Hand Dexterity: A Double-Blind RCT.Psychophysiology · 2025Trial
- The effect of transcranial random noise stimulation on the movement time and components of noise, co-variation, and tolerance in a perceptual-motor task.Scientific reports · 2025Trial
- Boosting executive functions and math abilities in adolescents with dyscalculia: the combined effect of prismatic adaptation and cognitive training.Frontiers in psychology · 2025Trial
- Performance after training in a complex cognitive task is enhanced by high-definition transcranial random noise stimulation.Scientific reports · 2022Trial
- Hemispheric Dissociation Revealed by Attentional Isolation and Transcranial Random Noise Stimulation.Journal of cognitive neuroscience · 2026Article
- [A review of noninvasive brain-computer interfaces combined with transcranial electrical stimulation for neural rehabilitation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Review
- A Mini-review on Unlocking Cognitive Enhancement: An Innovative Strategy for Optimal Brain Functions.Central nervous system agents in medicinal chemistry · 2026Review
- Effects of Transcranial Direct Current Stimulation (tDCS) on Cognition in Patients with Drug-Resistant Focal Epilepsy: A Critical Review.Advances in experimental medicine and biology · 2026Review
- Neuromodulation of Working Memory: Mechanisms, Targets, and Behavioral Outcomes.Neuroscience insights · 2026Review
- Double stochastic resonance in stink bug sexual communication.Scientific reports · 2025Article
- Non-invasive brain stimulation: current and future applications in neurology.Nature reviews. Neurology · 2025Review
- Modulating neuroplasticity for chronic pain relief: noninvasive neuromodulation as a promising approach.Experimental & molecular medicine · 2025Review
- Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models.Frontiers in neuroscience · 2025Review
- The impact of transcranial random noise stimulation (tRNS) on alpha coherence and verbal divergent thinking.Network neuroscience (Cambridge, Mass.) · 2025Article
- Transcranial Brain Stimulation for Neurodevelopmental Disorders : Neuromodulation and Neurodevelopmental Disorders.Galen medical journal · 2025Review
- Dissociable components of visual perceptual learning characterized by non-invasive brain stimulation: Stage 1 Registered Report.Brain communications · 2025Article
- Physical Therapy for Addiction.Advances in experimental medicine and biology · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial random noise stimulation (tRNS) is a recent neuromodulation protocol. The high-frequency band (hf-tRNS) has shown to be the most effective in enhancing neural excitability. The frequency band of hf-tRNS typically spans from 100 to 640 Hz. Here we asked whether both the lower and the higher half of the high-frequency band are needed for increasing neural excitability. Three frequency ranges (100-400 Hz, 400-700 Hz, 100-700 Hz) and Sham conditions were delivered for 10 minutes at an intensity of 1.5 mA over the primary motor cortex (M1). Single-pulse transcranial magnetic stimulation (TMS) was delivered over the same area at baseline, 0, 10, 20, 30, 45 and 60 minutes after stimulation, while motor evoked potentials (MEPs) were recorded to evaluate changes in cortical excitability. Only the full-band condition (100-700 Hz) was able to modulate excitability by enhancing MEPs at 10 and 20 minutes after stimulation: neither the higher nor the lower sub-range of the high-frequency band significantly modulated cortical excitability. These results show that the efficacy of tRNS is strictly related to the width of the selected frequency range.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.